# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4712495 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
2. | ALA4712496 | F | Antiproliferative activity against human MDA-MB-468 cells harbouring STAT3 assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
3. | ALA4712497 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
4. | ALA4712498 | A | Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
5. | ALA4712501 | B | Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain (unknown origin) preincubated for 30 mins followed by hSIE probe addition by EMSA analysis | Homo sapiens | 39 | single protein format | Scientific Literature | ||
6. | ALA4712502 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability at 2 uM incubated for 24 hrs by Trypan blue exclusion dye based phase contrast microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4712503 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability at 2 uM incubated for 24 hrs by Trypan blue exclusion dye based phase contrast microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4712504 | B | Binding affinity to STAT3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA4712505 | B | Binding affinity to STAT3 (unknown origin) assessed as change in gibbs free energy by isothermal titration calorimetry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA4712506 | B | Binding affinity to STAT3 (unknown origin) assessed as change in enthalpy by isothermal titration calorimetry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA4712507 | B | Binding affinity to STAT3 (unknown origin) assessed as change in entropy by isothermal titration calorimetry | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA4712508 | B | Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1/STAT3 heterodimer in mouse NIH3T3 nuclear extract preincubated for 30 mins followed by hSIE probe addition by EMSA analysis | Mus musculus | 5 | subcellular format | Scientific Literature | ||
13. | ALA4712509 | B | Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT1 homodimer in mouse NIH3T3 nuclear extract preincubated for 30 mins followed by hSIE probe addition by EMSA analysis | Mus musculus | 5 | subcellular format | Scientific Literature | ||
14. | ALA4712510 | B | Inhibition of oligonucleotide [32P]-labelled 5'-AGATTTCTAGGAATTCAA probe binding to STAT5 homodimer in mouse NIH3T3 nuclear extract preincubated for 30 mins followed by MGFe probe addition by EMSA analysis | Mus musculus | 5 | tissue-based format | Scientific Literature | ||
15. | ALA4712513 | B | Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA hSIE probe binding to STAT3 in human MDA-MB-468 cell nuclear extract at 5 uM by EMSA analysis | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
16. | ALA4712515 | B | Inhibition of STAT3 phosphorylation at Y705 residues in human MDA-MB-468 whole cell lysate at 3 uM at 24 hrs by immunoblotting analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
17. | ALA4712524 | F | Anticlonogenic activity against human MDA-MB-231 cells assessed as inhibition of colony formation at 0.5 to 1 uM incubated for 4 hrs by crystal violet staining based assay | Homo sapiens | 3 | cell-based format | Scientific Literature |