# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4774694 | F | Antagonist activity at human alpha1A receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium release incubated for 40 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA4774695 | F | Antagonist activity at human alpha1B receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium release incubated for 40 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA4774696 | F | Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium release incubated for 40 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
4. | ALA4774697 | B | Inhibition of 5-alpha reductase in rat liver microsomes assessed as inhibition of DHT formation using testosterone as substrate incubated for 10 mins by NADPH assay | Rattus norvegicus | 6 | microsome format | Scientific Literature |