# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4768747 | F | Antiviral activity against HIV-1 infected in FlpIn-HEK293 cells assessed as activation of long terminal repeat driven gene expression incubated for 72 hrs by luciferase based cellular assay | Human immunodeficiency virus 1 | 76 | ALA4765284 | organism-based format | Scientific Literature | |
2. | ALA4768748 | F | Antiviral activity against CMV infected in FlpIn-HEK293 cells assessed as click beetle green reporter driven gene expression incubated for 72 hrs by luciferase based cellular assay | Cytomegalovirus | 76 | ALA4765284 | organism-based format | Scientific Literature | |
3. | ALA4768749 | P | Aqueous solubility of compound at pH 2 by nephelometry | 13 | ALA4765284 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4768750 | P | Aqueous solubility of compound at pH 6.5 by nephelometry | 13 | ALA4765284 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4768751 | A | Metabolic stability in human liver microsomes assessed as half life at 1 uM measured upto 60 mins by LC-MS anlaysis | Homo sapiens | 13 | ALA4765284 | microsome format | Scientific Literature | |
6. | ALA4768752 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 60 mins by LC-MS analysis | Homo sapiens | 13 | ALA4765284 | microsome format | Scientific Literature | |
7. | ALA4768753 | A | Metabolic stability in mouse liver microsomes assessed as half life at 1 uM measured upto 60 mins by LC-MS anlaysis | Mus musculus | 13 | ALA4765284 | microsome format | Scientific Literature | |
8. | ALA4768754 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM measured upto 60 mins by LC-MS anlaysis | Mus musculus | 13 | ALA4765284 | microsome format | Scientific Literature | |
9. | ALA4768757 | F | Antiviral activity against HIV-1 infected in FlpIn-HEK293 cells assessed as maximal activation of long terminal repeat driven gene expression at 0.25 uM incubated for 48 hrs by luciferase based cellular assay relative to control | Human immunodeficiency virus 1 | 2 | ALA4765284 | organism-based format | Scientific Literature | |
10. | ALA4768763 | F | Antiviral activity against HIV-1 infected in J-Lat 10.6 cells assessed as maximal activation of long terminal repeat driven gene expression incubated for 48 hrs by green fluorescent protein based cellular assay | Human immunodeficiency virus 1 | 11 | ALA4765284 | organism-based format | Scientific Literature | |
11. | ALA4768765 | F | Antiviral activity against HIV-1 infected in J-Lat 10.6 cells assessed as maximal activation of long terminal repeat driven gene expression at 1 uM incubated for 48 hrs by green fluorescent protein based cellular assay relative to control | Human immunodeficiency virus 1 | 3 | ALA4765284 | organism-based format | Scientific Literature | |
12. | ALA4768769 | A | Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay | Homo sapiens | 11 | ALA4765284 | cell-based format | Scientific Literature | |
13. | ALA4768771 | B | Inhibition of CDK9 (unknown origin) at 0.5 uM | Homo sapiens | 2 | ALA4765284 | single protein format | Scientific Literature | |
14. | ALA4768772 | B | Inhibition of cyclin K (unknown origin) at 0.5 uM | Homo sapiens | 2 | ALA4765284 | single protein format | Scientific Literature | |
15. | ALA4768773 | B | Inhibition of cyclin T1 (unknown origin) at 0.5 uM | Homo sapiens | 2 | ALA4765284 | single protein format | Scientific Literature | |
16. | ALA4768774 | B | Inhibition of cyclin T2 (unknown origin) at 0.5 uM | Homo sapiens | 2 | ALA4765284 | single protein format | Scientific Literature |