# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731025 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR expressed in HEK293 cells at 10 uM by radio ligand binding assay relative to control | Homo sapiens | 8 | ALA4725439 | cell-based format | Scientific Literature | |
2. | ALA4731026 | B | Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assay | Mus musculus | 4 | ALA4725439 | cell-based format | Scientific Literature | |
3. | ALA4731028 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human A2A receptor expressed in HEK293 cells assessed as inhibitor constant by radio ligand binding assay | Homo sapiens | 3 | ALA4725439 | cell-based format | Scientific Literature | |
4. | ALA4731030 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes assessed as inhibitor constant by radio ligand binding assay | Homo sapiens | 8 | ALA4725439 | cell-based format | Scientific Literature | |
5. | ALA4731031 | B | Displacement of [125I]AB-MECA from mouse adrenergic A3 receptor expressed in HEK293 cell membranes assessed as inhibitor constant by radio ligand binding assay | Mus musculus | 8 | ALA4725439 | cell-based format | Scientific Literature | |
6. | ALA4731036 | A | Stability in Sprague-Dawley rat plasma | Rattus norvegicus | 5 | ALA4725439 | cell-free format | Scientific Literature | |
7. | ALA4731037 | A | Stability in Sprague-Dawley rat liver microsomes | Rattus norvegicus | 5 | ALA4725439 | microsome format | Scientific Literature | |
8. | ALA4731038 | A | Cytotoxicity against human HepG2 cells | Homo sapiens | 5 | ALA4725439 | cell-based format | Scientific Literature | |
9. | ALA4731039 | A | Oral bioavailability in Sprague-Dawley rat | Rattus norvegicus | 5 | ALA4725439 | organism-based format | Scientific Literature | |
10. | ALA4731040 | B | Displacement of [3H]CGS21680 from mouse A2A receptor expressed in HEK293 cells at 10 uM by radio ligand binding assay relative to control | Mus musculus | 5 | ALA4725439 | cell-based format | Scientific Literature | |
11. | ALA5233323 | B | Binding affinity to human adenosine A1 receptor assessed as inhibition constant | Homo sapiens | 2 | ALA5233204 | single protein format | Scientific Literature |