#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4733961	B	Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation at 25 uM preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis relative to control	Homo sapiens	44		single protein format	Scientific Literature
2.	ALA4733962	F	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation at 100 uM incubated for 48 hrs by CCK-8 assay relative to control	Homo sapiens	44		cell-based format	Scientific Literature
3.	ALA4733963	B	Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis	Homo sapiens	5		single protein format	Scientific Literature
4.	ALA4733964	F	Antiproliferative activity against human A549 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	5		cell-based format	Scientific Literature
5.	ALA4733965	F	Antiproliferative activity against human H1299 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	5		cell-based format	Scientific Literature
6.	ALA4733966	A	Cytotoxicity against human 16H6E cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	5		cell-based format	Scientific Literature
7.	ALA4733967	A	Cytotoxicity against human BEAS-2B cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	5		cell-based format	Scientific Literature
8.	ALA4733968	B	Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin1-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
9.	ALA4733969	B	Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin2-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4733970	B	Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin4a-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4733971	B	Inhibition of NAE-mediated neddylation in human A549 cells assessed as suppression of cullin5-Nedd8 adduct formation at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4733972	B	Inhibition of NAE-mediated UBE2M neddylation in human A549 cells at 12.5 to 25 uM measured after 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4733973	F	Induction of Wee1 accumulation in human A549 cells at 50 uM incubated for 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4733974	F	Induction of p27 accumulation in human A549 cells at 50 uM incubated for 6 to 12 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
15.	ALA4733975	F	Induction of apoptosis in human A549 cells assessed as increase in PARP cleavage at 12.5 uM by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
16.	ALA4733976	F	Induction of apoptosis in human A549 cells assessed as increase in ratio of early and late apoptotic cells at 10 to 40 uM after 48 hrs by Annexin V-FITC/PI double staining based flow cytometric analysis (Rvb = 2.6%)	Homo sapiens	1		cell-based format	Scientific Literature
17.	ALA4733977	F	Induction of cellular senescence in human A549 cells at 10 uM by SA-beta-gal-staining based assay	Homo sapiens	1		cell-based format	Scientific Literature
18.	ALA4733978	F	Antitumor activity against human A549 cells xenografted in nude mouse assessed as decrease in tumor weight at 30 mg/kg, ip qd for 5 days on and 2 days off dosing and measured after 24 days post-treatment	Homo sapiens	1		organism-based format	Scientific Literature
19.	ALA4733979	F	Antitumor activity against human A549 cells xenografted in nude mouse assessed as decrease in tumor volume at 30 mg/kg, ip qd for 5 days on and 2 days off dosing and measured after 24 days post-treatment	Homo sapiens	1		organism-based format	Scientific Literature
20.	ALA4733980	F	Antitumor activity against human A549 cells xenografted in nude mouse assessed as inhibition of tumor growth at 60 mg/kg, po qd for 5 days on and 2 days off dosing and measured after 24 days post-treatment	Homo sapiens	1		organism-based format	Scientific Literature