# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4769875 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 10 | ALA4765317 | organism-based format | Scientific Literature | |
2. | ALA4769876 | Functional | Antibacterial activity against Staphylococcus aureus USA300 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 11 | ALA4765317 | organism-based format | Scientific Literature | |
3. | ALA4769877 | Functional | Antibacterial activity against cystic fibrosis patient isolate Staphylococcus aureus assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 11 | ALA4765317 | organism-based format | Scientific Literature | |
4. | ALA4769878 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus DRL-3161 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 3 | ALA4765317 | organism-based format | Scientific Literature | |
5. | ALA4769879 | Functional | Antibacterial activity against Streptococcus pyogenes LSI-1235 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Streptococcus pyogenes | 3 | ALA4765317 | organism-based format | Scientific Literature | |
6. | ALA4769880 | Functional | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae LSI-4234 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Streptococcus pneumoniae | 3 | ALA4765317 | organism-based format | Scientific Literature | |
7. | ALA4769881 | Functional | Antibacterial activity against penicillin-resistant Streptococcus pneumoniae LSI-4246 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Streptococcus pneumoniae | 3 | ALA4765317 | organism-based format | Scientific Literature | |
8. | ALA4769882 | Functional | Antibacterial activity against Vancomycin-susceptible Enterococcus faecium DRL-4193 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Enterococcus faecium | 3 | ALA4765317 | organism-based format | Scientific Literature | |
9. | ALA4769883 | Functional | Antibacterial activity against Vancomycin-resistant Enterococcus faecium LSI-3340 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Enterococcus faecium | 3 | ALA4765317 | organism-based format | Scientific Literature | |
10. | ALA4769884 | Functional | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Enterococcus faecalis | 3 | ALA4765317 | organism-based format | Scientific Literature | |
11. | ALA4769885 | Functional | Antibacterial activity against Fluoroquinolone-resistant Staphylococcus aureus assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 2 | ALA4765317 | organism-based format | Scientific Literature | |
12. | ALA4769886 | Functional | Potency index, ratio of MIC90 of ciprofloxacin to MIC90 of compound for antibacterial activity against Fluoroquinolone-resistant Staphylococcus aureus assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 1 | ALA4765317 | organism-based format | Scientific Literature | |
13. | ALA4769887 | Binding | Inhibition of Staphylococcus aureus DNA gyrase using positively supercoiled pBR322 DNA as substrate incubated for 30 mins by agarose gel electrophoresis method | Staphylococcus aureus | 6 | ALA4765317 | assay format | Scientific Literature | |
14. | ALA4769888 | Binding | Inhibition of Staphylococcus aureus topoisomerase IV using kDNA as substrate incubated for 30 mins by gel electrophoresis analysis | Staphylococcus aureus | 6 | ALA4765317 | assay format | Scientific Literature | |
15. | ALA4769889 | Binding | Selectivity index, ratio of IC50 for inhibition of Staphylococcus aureus topoisomerase IV to IC50 for inhibition of Staphylococcus aureus DNA gyrase | Staphylococcus aureus | 5 | ALA4765317 | assay format | Scientific Literature | |
16. | ALA4769890 | Functional | Antibacterial activity against Staphylococcus aureus 3527 assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 6 | ALA4765317 | organism-based format | Scientific Literature | |
17. | ALA4769891 | Functional | Antibacterial activity against Staphylococcus aureus harboring DNA gyrase D83N mutant assessed as reduction in bacterial growth by CLSI based broth microdilution method | Staphylococcus aureus | 6 | ALA4765317 | organism-based format | Scientific Literature | |
18. | ALA4769892 | Functional | Selectivity index, ratio of MIC for Staphylococcus aureus 3527 to MIC for Staphylococcus aureus harboring DNA gyrase D83N mutant | Staphylococcus aureus | 6 | ALA4765317 | assay format | Scientific Literature | |
19. | ALA4769893 | Binding | Inhibition of human ERG | Homo sapiens | 12 | ALA4765317 | single protein format | Scientific Literature | |
20. | ALA4769894 | Binding | Inhibition of recombinant human ERG expressed in CHO-K1 cells at 3 uM at -80 mV holding potential by automated Qpatch clamp assay relative to control | Homo sapiens | 1 | ALA4765317 | cell-based format | Scientific Literature |