| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4719396 | B | Binding affinity to STAT3 K591A mutant (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 2. | ALA4719397 | F | Antiproliferative activity against human MDA-MB-468 cells harboring active STAT3 assessed as reduction in cell growth incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 3. | ALA4719398 | F | Antiproliferative activity against human MDA-MB-231 cells harboring active STAT3 assessed as reduction in cell growth incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 4. | ALA4719399 | F | Antiproliferative activity against human DU-145 cells harboring active STAT3 assessed as reduction in cell growth incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 5. | ALA4719400 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 6. | ALA4719401 | B | Binding affinity to STAT3 (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 7. | ALA4719402 | B | Binding affinity to STAT3 R595G mutant (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 8. | ALA4719403 | B | Binding affinity to STAT3 C712G mutant (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 9. | ALA4719404 | B | Binding affinity to STAT3 K591A/S611G mutant (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 10. | ALA4719405 | B | Binding affinity to STAT3 I643S/Q635G mutant (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature | |
| 11. | ALA4719406 | B | Inhibition of STAT3-dependent transcriptional activity in human HeLa cells transfected with p-Luc-TKS3 assessed as reduction in luciferase expression incubated for 24 hrs by dual luciferase reporter gene assay | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 12. | ALA4719407 | B | Inhibition of STAT3 in human MDA-MB-468 cells assessed as reduction in STAT3 Y705 residue phosphorylation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 13. | ALA4719408 | F | Effect on STAT3 expression in human MDA-MB-468 cells at 1 to 30 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 14. | ALA4719409 | B | Inhibition of STAT1 in human MDA-MB-468 cells assessed as reduction in STAT1 phosphorylation at 1 to 30 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 15. | ALA4719410 | B | Inhibition of STAT5 in human MDA-MB-468 cells assessed as reduction in STAT5 phosphorylation at 1 to 30 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 16. | ALA4719411 | B | Inhibition of STAT3 in human MDA-MB-468 cells assessed as reduction in Bcl-XL expression at 1 to 30 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 17. | ALA4719412 | F | Antimigratory activity against human MDA-MB-468 cells assessed as reduction in cell migration incubated for 24 hrs by transwell study based analysis | Homo sapiens | 1 | ALA4715784 | cell-based format | Scientific Literature | |
| 18. | ALA4719413 | B | Displacement of fluorescein-labeled pYLPQTV-NH2 from STAT3 SH2 domain (unknown origin) by fluorescence polarization assay | Homo sapiens | 1 | ALA4715784 | single protein format | Scientific Literature | |
| 19. | ALA4719414 | B | Selectivity ratio of Kd for STAT3 I643S/Q635G mutant (unknown origin) expressed in Escherichia coli to Kd for wild type STAT3 (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assay | Homo sapiens | 1 | ALA4715784 | assay format | Scientific Literature |
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