#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4701888	F	Antiproliferative activity against human KYSE-520 cells	Homo sapiens	20	ALA4699491	cell-based format	Scientific Literature
2.	ALA4701889	B	Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY122 incubated for 30 mins by fluorescence based DIFMUP assay	Homo sapiens	29	ALA4699491	assay format	Scientific Literature
3.	ALA4701891	B	Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ERK1/2 phosphorylation by fluorescence based assay	Homo sapiens	20	ALA4699491	cell-based format	Scientific Literature
4.	ALA4701899	P	Aqueous solubility of the compound at pH 6.8		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
5.	ALA4701900	P	Lipophilicity, logP of the compound		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
6.	ALA4701901	P	Distribution coefficient, logD of the compound		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
7.	ALA4701902	B	Inhibition of human ERG by Q-patch assay	Homo sapiens	18	ALA4699491	single protein format	Scientific Literature
8.	ALA5145443	B	Allosteric inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP and 2p-IRS1 peptide as substrates preincubated for 1 hr and followed by substrate addition at 10 uM and measured by microplate reader method relative to control	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature
9.	ALA5145444	B	Allosteric inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP and 2p-IRS1 peptide as substrates preincubated for 1 hr and followed by substrate addition and measured by microplate reader method	Homo sapiens	57	ALA5143569	single protein format	Scientific Literature
10.	ALA5145445	B	Allosteric inhibition of recombinant human SHP2 PTP domain (237 to 535 residues) using DiFMUP as substrate preincubated for 30 mins and followed by substrate addition and measured by microplate reader method	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature
11.	ALA5145446	B	Allosteric inhibition of recombinant human SHP2 assessed as change in melting temperature by SYPRO orange dye based thermal shift assay	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature
12.	ALA5145447	B	Reversible inhibition of wild-type human SHP2 using DiFMUP as substrate and measured by jump dilution assay	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
13.	ALA5145448	B	Inhibition of wild-type SHP1 (2 to 595 residues) (unknown origin) using DiFMUP as substrate and measured by biochemical assay	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
14.	ALA5145449	B	Inhibition of wild-type PTP1B (2 to 435 residues) (unknown origin) using DiFMUP as substrate and measured by biochemical assay	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
15.	ALA5145450	B	Reversible inhibition of wild-type human SHP2 using DiFMUP as substrate assessed as recovery of SHP2 phosphatase activity and measured by jump dilution assay	Homo sapiens	1	ALA5143569	single protein format	Scientific Literature
16.	ALA5145451	B	Non-competitive inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP as substrate assessed as Vmax at 0.032 uM measured by Lineweaver-Burk plot analysis	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
17.	ALA5145452	B	Non-competitive inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP as substrate assessed as Vmax at 0.08 uM measured by Lineweaver-Burk plot analysis	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
18.	ALA5145453	B	Non-competitive inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP as substrate assessed as Vmax at 0.2 uM measured by Lineweaver-Burk plot analysis	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
19.	ALA5145454	B	Non-competitive inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP as substrate assessed as Km at 0.032 uM measured by Lineweaver-Burk plot analysis	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature
20.	ALA5145455	B	Non-competitive inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP as substrate assessed as Km at 0.08 uM measured by Lineweaver-Burk plot analysis	Homo sapiens	2	ALA5143569	single protein format	Scientific Literature