# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4711062 | A | Effect on swimming speed in ICR mouse model of scopolamine-induced memory impairment at 15 mg/kg, po administered 30 mins prior to scopolamine injection by Morris water maze test | Mus musculus | 2 | ALA4706588 | organism-based format | Scientific Literature | |
2. | ALA4711063 | F | Cognitive enhancing effect in ICR mouse model of scopolamine-induced memory impairment assessed as reduction in distance travelled to found target at 15 mg/kg, po administered 30 mins prior to scopolamine injection by Morris water maze test | Mus musculus | 3 | ALA4706588 | organism-based format | Scientific Literature | |
3. | ALA4711064 | F | Cognitive enhancing effect in ICR mouse model of scopolamine-induced memory impairment assessed as reduction in time spent to found target at 15 mg/kg, po administered 30 mins prior to scopolamine injection by Morris water maze test | Mus musculus | 3 | ALA4706588 | organism-based format | Scientific Literature | |
4. | ALA4711065 | F | Inhibition of LPS-induced ROS production in mouse BV-2 cells at 5 uM incubated for 1 hr followed by LPS stimulation and measured after 24 hrs by DCFH-DA staining based inverted fluorescence microscopic analysis | Mus musculus | 2 | ALA4706588 | cell-based format | Scientific Literature | |
5. | ALA4711066 | B | Inhibition of GSK3beta in mouse N2a cells overexpressing human tau protein assessed as phosphorylated tau Ser396 residue level at 15 uM incubated for 1 hr followed by okadaid-acid addition and measured after 5 hrs by Western blot analysis relative to control | Mus musculus | 1 | ALA4706588 | cell-based format | Scientific Literature | |
6. | ALA4711067 | B | Inhibition of GSK3beta in mouse N2a cells overexpressing human tau protein assessed as reduction in tau Ser396 residue phosphorylation at 5 uM incubated for 1 hr followed by okadaid-acid addition and measured after 5 hrs by Western blot analysis relative to control | Mus musculus | 1 | ALA4706588 | cell-based format | Scientific Literature | |
7. | ALA4711068 | B | Inhibition of DYRK1alpha (unknown origin) | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
8. | ALA4711069 | B | Inhibition of DYRK1beta (unknown origin) | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
9. | ALA4711070 | B | Inhibition of ERK1 (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
10. | ALA4711071 | B | Inhibition of ERK2 (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
11. | ALA4711072 | B | Inhibition of P38alpha (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
12. | ALA4711073 | B | Inhibition of GSK-3alpha (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
13. | ALA4711074 | B | Inhibition of GSK-3beta (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
14. | ALA4711075 | B | Inhibition of P38delta (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
15. | ALA4711076 | B | Inhibition of P38gamma (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
16. | ALA4711077 | B | Inhibition of DYRK1beta (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
17. | ALA4711078 | B | Inhibition of DYRK1alpha (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
18. | ALA4711079 | B | Inhibition of JNK3 (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
19. | ALA4711080 | B | Inhibition of JNK2 (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature | |
20. | ALA4711081 | B | Inhibition of CDK2 (unknown origin) at 300 nM relative to control | Homo sapiens | 1 | ALA4706588 | single protein format | Scientific Literature |