#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4765504	B	Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene-based spectrophotometric method	Homo sapiens	40	ALA4765226	cell-based format	Scientific Literature
2.	ALA4765505	B	Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by measuring maximal response by quanti-blue SEAP reporter gene-based spectrophotometric method	Homo sapiens	41	ALA4765226	cell-based format	Scientific Literature
3.	ALA4765506	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of TNFalpha production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
4.	ALA4765507	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of IL-1beta production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
5.	ALA4765508	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of IL-6 production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
6.	ALA4765509	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of IL-12p40 production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
7.	ALA4765510	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of IFNgamma production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
8.	ALA4765511	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of MCP1 production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
9.	ALA4765512	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of MIP-1alpha production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
10.	ALA4765513	B	Agonist activity at TLR8 in human PBMC cells assessed as induction of MIP-1beta production incubated for 16 hrs by immunoassay	Homo sapiens	3	ALA4765226	cell-based format	Scientific Literature
11.	ALA4765516	B	Agonist activity at TLR8 in human monocytes assessed as induction of NF-kappaB phosphorylation at p65 subunit measured after 15 mins in presence of 10% FBS by Alexa fluor 647 dye based flow cytometry analysis	Homo sapiens	2	ALA4765226	cell-based format	Scientific Literature
12.	ALA4765517	B	Agonist activity at TLR8 in human polymorphonuclear leucocyte cells assessed as induction of NF-kappaB phosphorylation at p65 subunit measured after 15 mins in presence of 10% FBS by Alexa fluor 647 dye based flow cytometry analysis	Homo sapiens	2	ALA4765226	tissue-based format	Scientific Literature
13.	ALA4765518	B	Agonist activity at human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
14.	ALA4765519	B	Agonist activity at human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
15.	ALA4765520	B	Agonist activity at human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
16.	ALA4765521	B	Agonist activity at human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
17.	ALA4765522	B	Agonist activity at human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
18.	ALA4765523	B	Agonist activity at human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method	Homo sapiens	43	ALA4765226	cell-based format	Scientific Literature
19.	ALA5227818	B	Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter gene based spectrophotometric assay	Homo sapiens	7	ALA5226312	cell-based format	Scientific Literature