# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701743 | Binding | Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP HiLyte 647 tracer bound ADP2 antibody-Tb conjugate based HTRF assay | Homo sapiens | 13 | ALA4699485 | assay format | Scientific Literature | |
2. | ALA4701744 | Functional | Antiproliferative activity against human A2780 cells after 48 hrs by MTT assay | Homo sapiens | 13 | ALA4699485 | cell-based format | Scientific Literature | |
3. | ALA4701746 | Binding | Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4699485 | assay format | Scientific Literature | |
4. | ALA4701747 | Functional | Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4699485 | cell-based format | Scientific Literature | |
5. | ALA4701748 | Functional | Antiproliferative activity against human SK-OV-3 cells after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4699485 | cell-based format | Scientific Literature |