# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4717197 | Functional | Cytotoxicity against human MES-SA cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 27 | ALA4715714 | cell-based format | Scientific Literature | |
2. | ALA4717198 | Functional | Cytotoxicity against human MES-SA/DX5 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 27 | ALA4715714 | cell-based format | Scientific Literature | |
3. | ALA4717199 | Functional | Cytotoxicity against human MES-SA cells transfected with mCherry fluorescent protein assessed as inhibition of cell proliferation incubated for 72 hrs by fluorescent assay | Homo sapiens | 50 | ALA4715714 | cell-based format | Scientific Literature | |
4. | ALA4717200 | Functional | Cytotoxicity against human MES-SA/DX5 cells transfected with mCherry fluorescent protein assessed as inhibition of cell proliferation incubated for 72 hrs by fluorescent assay | Homo sapiens | 48 | ALA4715714 | cell-based format | Scientific Literature | |
5. | ALA4717201 | Functional | Cytotoxicity against human KB-3-1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4715714 | cell-based format | Scientific Literature | |
6. | ALA4717202 | Functional | Cytotoxicity against human KB-V1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA4715714 | cell-based format | Scientific Literature | |
7. | ALA4717203 | Functional | Cytotoxicity against human A2780 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 20 | ALA4715714 | cell-based format | Scientific Literature | |
8. | ALA4717204 | Functional | Cytotoxicity against human A2780adr cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 20 | ALA4715714 | cell-based format | Scientific Literature | |
9. | ALA4717205 | Functional | Cytotoxicity against human MES-SA/DX5 cells incubated for 72 hrs in presence of efflux pump inhibitor, Tariquidar by MTT assay | Homo sapiens | 14 | ALA4715714 | cell-based format | Scientific Literature | |
10. | ALA4717206 | ADME | Cytotoxicity against human HFF cells by Prestoblue assay | Homo sapiens | 8 | ALA4715714 | cell-based format | Scientific Literature | |
11. | ALA4717209 | Functional | Selectivity ratio of IC50 for human MES-SA cells to IC50 for human MES-SA/DX5 cells incubated for 72 hrs by MTT assay | Homo sapiens | 16 | ALA4715714 | assay format | Scientific Literature | |
12. | ALA4808312 | Binding | Binding affinity to Zn(II)+ incubated for 60 mins using RhodZin-3 by fuorescence assay | 30 | ALA4808163 | assay format | Scientific Literature | ||
13. | ALA4808313 | Binding | Binding affinity to Zn(II)+ incubated for 60 mins using FluoZin-3 by fuorescence assay | 29 | ALA4808163 | assay format | Scientific Literature | ||
14. | ALA4808314 | Functional | Growth inhibition of human TOV112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay | Homo sapiens | 29 | ALA4808163 | cell-based format | Scientific Literature | |
15. | ALA4808315 | Functional | Ratio of EC50 for test compound to EC50 for ZMC1 for growth inhibition of human TOV-112D cells harbouring p53 R175H mutant incubated for 3 days by MTS assay | Homo sapiens | 29 | ALA4808163 | tissue-based format | Scientific Literature | |
16. | ALA4808316 | Functional | Induction of ROS production in human H1299 cells at 0.75 uM incubated for 24 hrs by CellRox green based fluorescence flow cytometry relative to ZMC1 | Homo sapiens | 29 | ALA4808163 | cell-based format | Scientific Literature | |
17. | ALA4808317 | ADME | Apparent permeability in human Caco-2 cells at 5 uM measured up to 90 mins by LC-MS/MS analysis | Homo sapiens | 29 | ALA4808163 | cell-based format | Scientific Literature | |
18. | ALA4808318 | Binding | Induction of Zinc-dependent p53 R175H mutant refolding by assessing wild type conformation | 29 | ALA4808163 | assay format | Scientific Literature | ||
19. | ALA4808319 | Functional | Cytotoxicity against human NCI-H460 cells harbouring p53 wild type | Homo sapiens | 2 | ALA4808163 | cell-based format | Scientific Literature | |
20. | ALA4808320 | Functional | Cytotoxicity against p53-null human H1299 cells | Homo sapiens | 2 | ALA4808163 | cell-based format | Scientific Literature |