| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4731830 | B | Displacement of [125I]SDF-1alpha from CXCR4 in human Chem-1 cells measured after 90 mins | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4731831 | F | Antagonist activity at CXCR4 (unknown origin) expressed in CHO cells assessed as reduction in SDF1-induced intracellular calcium mobilization incubated for 15 mins followed by SDF1 addition by Fluo-AM dye based fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4731833 | B | Inhibition of HIV1 3B reverse transcriptase infected in human GHOST CXCR4 cells assessed as reduction in viral replication incubated for 60 to 90 mins in presence of DTT and TTP by liquid scintillation counter | Human immunodeficiency virus 1 | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4731834 | A | Cytotoxicity against human GHOST CXCR4 cells assessed as reduction in cell viability incubated for 4 hrs by XTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4731835 | T | Therapeutic index, ratio of TC50 for human GHOST CXCR4 cells assessed as reduction in cell viability incubated for 4 hrs by XTT assay to EC50 for HIV1 3B reverse transcriptase infected in human GHOST CXCR4 cells assessed as reduction in viral replication incubated for 60 to 90 mins in presence of DTT and TTP by liquid scintillation counter | 3 | cell-based format | Scientific Literature |
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