# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4684894 | Binding | Binding affinity to human 5HT2C expressed in CHO cells | Homo sapiens | 14 | ALA4680188 | cell-based format | Scientific Literature | |
2. | ALA4684895 | Binding | Displacement of 2-[125l]-lodomelatonin from human MT1 expressed in CHO cells incubated for 120 mins by radioligand binding assay | Homo sapiens | 15 | ALA4680188 | cell-based format | Scientific Literature | |
3. | ALA4684896 | Binding | Displacement of 2-[125l]-lodomelatonin from human MT2 expressed in CHO cells incubated for 120 mins by radioligand binding assay | Homo sapiens | 15 | ALA4680188 | cell-based format | Scientific Literature | |
4. | ALA4684897 | Functional | Agonist activity at human MT1 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assay | Homo sapiens | 11 | ALA4680188 | cell membrane format | Scientific Literature | |
5. | ALA4684898 | Functional | Agonist activity at human MT1 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assay relative to control | Homo sapiens | 11 | ALA4680188 | cell membrane format | Scientific Literature | |
6. | ALA4684899 | Functional | Agonist activity at human MT2 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assay | Homo sapiens | 11 | ALA4680188 | cell membrane format | Scientific Literature | |
7. | ALA4684900 | Functional | Agonist activity at human MT2 expressed in CHO cell membrane incubated for 1 hr by [35S]GTPgammaS binding assay relative to control | Homo sapiens | 11 | ALA4680188 | cell membrane format | Scientific Literature | |
8. | ALA4684901 | ADME | Oral bioavailability in rat | Rattus norvegicus | 10 | ALA4680188 | organism-based format | Scientific Literature | |
9. | ALA4684902 | ADME | Oral bioavailability in human | Homo sapiens | 10 | ALA4680188 | organism-based format | Scientific Literature | |
10. | ALA4684903 | ADME | Permeability in human Caco-2 cells | Homo sapiens | 10 | ALA4680188 | cell-based format | Scientific Literature |