| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4712920 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as suppression of 5-HT levels in serum at 10 mg/kg, ip dosed daily for 1 week by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4712921 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as suppression of 5-HT levels in brain at 10 mg/kg, ip dosed daily for 1 week by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA4712922 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as suppression of 5-HT levels in serum at 10 mg/kg, ip dosed daily for 8 weeks by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4712923 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as suppression of body weight gain at 10 mg/kg, ip dosed daily for 8 weeks by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4712924 | F | Anti-obesity activity in overnight fasted C57BL/6J mouse model of diet-induced obesity assessed as improvement in glucose tolerance at 1 to 10 mg/kg, ip by intraperitoneal glucose tolerance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4712925 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as suppression of fat mass at 10 mg/kg, ip dosed daily for 8 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA4712926 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as increase in lean body mass at 10 mg/kg, ip dosed daily for 8 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4712927 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipose tissues by measuring eWAT at 10 mg/kg, ip dosed daily for 8 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4712928 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipose tissues by measuring iWAT at 10 mg/kg, ip dosed daily for 8 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4712929 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipose tissues by measuring BAT at 10 mg/kg, ip dosed daily for 8 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4712930 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipose tissue inflammation at 10 mg/kg, ip dosed daily for 8 weeks by H and E staining based histological analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4712931 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipocyte size in eWAT at 10 mg/kg, ip dosed daily for 8 weeks by H and E staining based histological analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4712932 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in adipocyte size in iWAT at 10 mg/kg, ip dosed daily for 8 weeks by H and E staining based histological analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4712933 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as reduction in lipid droplet size at 10 mg/kg, ip dosed daily for 8 weeks by H and E staining based histological analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4712934 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as increase in multilocular adipocytes at 10 mg/kg, ip dosed daily for 8 weeks by H and E staining based histological analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4712935 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as increase in VO2 at 10 mg/kg, ip dosed daily for 8 weeks by indirect calorimetry | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4712936 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as increase in VCO2 at 10 mg/kg, ip dosed daily for 8 weeks by indirect calorimetry | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4712937 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as increase in heat production at 10 mg/kg, ip dosed daily for 8 weeks by indirect calorimetry | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4712938 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as effect on RER at 10 mg/kg, ip dosed daily for 8 weeks by indirect calorimetry | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4712939 | F | Anti-obesity activity in C57BL/6J mouse model of diet-induced obesity assessed as induction of thermogenic activity by measuring increase in Ucp1 mRNA expression in BAT at 10 mg/kg, ip dosed daily for 8 weeks by RT-PCR analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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