| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4710642 | Binding | Inhibition of recombinant human N-terminal His-tagged SphK2 (2 to 654 residues) expressed in baculovirus infected Sf21 cells at 125 uM using d-erythro-sphingosine as substrate incubated for 1 hr by ADP-Glo assay relative to control | Homo sapiens | 16 | ALA4706570 | cell-based format | Scientific Literature | |
| 2. | ALA4710643 | Binding | Inhibition of recombinant human SphK1 at 125 uM using d-erythro-sphingosine as substrate incubated for 1 hr by ADP-Glo assay relative to control | Homo sapiens | 19 | ALA4706570 | single protein format | Scientific Literature | |
| 3. | ALA4710644 | Binding | Inhibition of recombinant human N-terminal His-tagged SphK2 (2 to 654 residues) expressed in baculovirus infected Sf21 cells using d-erythro-sphingosine as substrate incubated for 1 hr by ADP-Glo assay | Homo sapiens | 15 | ALA4706570 | cell-based format | Scientific Literature | |
| 4. | ALA4710645 | Functional | Cytotoxicity against human U-251MG cells assessed as reduction in cell viability at 125 uM incubated for 24 hrs by Hoechst 33258 and PI staining based imaging analysis | Homo sapiens | 8 | ALA4706570 | cell-based format | Scientific Literature |
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