# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731698 | B | Inhibition of full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
2. | ALA4731699 | B | Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
3. | ALA4731700 | B | Selectivity ratio of IC50 for full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system to IC50 full length N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system | Homo sapiens | 12 | assay format | Scientific Literature | ||
4. | ALA4731701 | B | Inhibition of human recombinant HDAC8 expressed in Escherichia coli using Fluor de Lys substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence assay | 4 | assay format | Scientific Literature | |||
5. | ALA4731708 | F | Antiproliferative activity against human Ca9-22 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue dye based spectrofluorometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA4731709 | F | Antiproliferative activity against human TR-146 cells assessed as reduction in cell viability measured after 48 hrs by alamar blue dye based spectrofluorometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA4731710 | F | Antiproliferative activity against human U266B cells assessed as reduction in cell viability measured after 24 to 48 hrs by alamar blue dye based fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature |