# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4775955 | Functional | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as inhibition of bacterial growth measured after 16 hrs by agar plate dilution method | Enterococcus faecalis | 10 | ALA4765495 | organism-based format | Scientific Literature | |
2. | ALA4775962 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as inhibition of bacterial growth measured after 16 hrs by agar plate dilution method | Staphylococcus aureus | 18 | ALA4765495 | organism-based format | Scientific Literature | |
3. | ALA4775963 | Functional | Antibacterial activity against methicillin sensitive Staphylococcus aureus assessed as inhibition of bacterial growth measured after 16 hrs by agar plate dilution method | Staphylococcus aureus | 18 | ALA4765495 | organism-based format | Scientific Literature | |
4. | ALA4775964 | Functional | Antibacterial activity against methicillin resistant Staphylococcus aureus assessed as inhibition of bacterial growth measured after 16 hrs by agar plate dilution method | Staphylococcus aureus | 18 | ALA4765495 | organism-based format | Scientific Literature | |
5. | ALA4775965 | Binding | Inhibition of Staphylococcus aureus FabH A81V/A111T mutant assessed as bacterial growth inhibition measured after 18 hrs by resazurin dye based broth dilution assay | Staphylococcus aureus | 11 | ALA4765495 | assay format | Scientific Literature | |
6. | ALA4775966 | Binding | Inhibition of Staphylococcus aureus FabH A81V mutant assessed as bacterial growth inhibition measured after 18 hrs by resazurin dye based broth dilution assay | Staphylococcus aureus | 10 | ALA4765495 | assay format | Scientific Literature | |
7. | ALA4775967 | Functional | Antibacterial activity against methicillin resistant Staphylococcus aureus assessed as inhibition of bacterial growth measured after 18 hrs in presence of 10% human serum by resazurin dye based broth dilution assay | Staphylococcus aureus | 9 | ALA4765495 | organism-based format | Scientific Literature | |
8. | ALA4775968 | Functional | Antibacterial activity against Escherichia coli harboring delta tolC mutant assessed as inhibition of bacterial growth measured after 16 hrs by agar plate dilution method | Escherichia coli | 10 | ALA4765495 | organism-based format | Scientific Literature | |
9. | ALA4775969 | Binding | Binding affinity to His6-tagged Staphylococcus aureus FabF expressed in Escherichia coli BL21 (DE3) assessed as decrease in melting temperature at 10 uM by SYPRO orange based differential scanning fluorimetry | Staphylococcus aureus | 15 | ALA4765495 | assay format | Scientific Literature | |
10. | ALA4775970 | Binding | Binding affinity to His6-tagged Escherichia coli FabH expressed in Escherichia coli BL21 (DE3) assessed as decrease in melting temperature at 10 uM by SYPRO orange based differential scanning fluorimetry | Escherichia coli | 15 | ALA4765495 | assay format | Scientific Literature | |
11. | ALA4775979 | Functional | Antibacterial activity against methicillin resistant Staphylococcus aureus infected in C57BL/6J mouse model of peritonitis assessed as mouse survival when infected with 2.5x10^7 CFU bacteria at 10 mg/kg, ip administered at 1 and 5 hrs post infection | Staphylococcus aureus | 3 | ALA4765495 | organism-based format | Scientific Literature |