# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4682224 | Binding | Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISA | Homo sapiens | 41 | ALA4680114 | single protein format | Scientific Literature | |
2. | ALA4682225 | Binding | Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assay | Homo sapiens | 41 | ALA4680114 | cell-based format | Scientific Literature | |
3. | ALA4682226 | Physicochemical | Kinetic solubility in pH 7.4 PBS buffer by LC-UV assay | 41 | ALA4680114 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4682227 | ADME | Efflux ratio in MDCK-MDR1 cells incubated for 1 hr by LC-MS/MS analysis | Canis lupus familiaris | 41 | ALA4680114 | cell-based format | Scientific Literature | |
5. | ALA4682228 | ADME | Apparent permeability in MDCK-MDR1 cells incubated for 1 hr by LC-MS/MS analysis | Canis lupus familiaris | 41 | ALA4680114 | cell-based format | Scientific Literature |