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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4705217 A Enzymatic stability assessed as bovine pancreatic alpha-chymotrypsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis Bos taurus 15 single protein format Scientific Literature 2. ALA4705218 A Enzymatic stability assessed as porcine type 4 pancreatic elastase-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis Sus scrofa 15 single protein format Scientific Literature 3. ALA4705219 A Enzymatic stability assessed as porcine pepsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis Sus scrofa 15 assay format Scientific Literature 4. ALA4705220 A Enzymatic stability assessed as bovine pancreatic trypsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis Bos taurus 15 assay format Scientific Literature 5. ALA4705221 A Half life in C57BL/6 mouse whole blood at 100 uM by LC-MS/MS analysis Mus musculus 15 tissue-based format Scientific Literature 6. ALA4705222 A Half life in cynomolgus monkey whole blood at 100 uM by LC-MS/MS analysis Macaca fascicularis 15 tissue-based format Scientific Literature 7. ALA4705223 B Inhibition of AlexaFluor647-tagged cyclic peptide binding to avi-tagged-biotinylated human PCSK9 measured after 2 hrs by Lance Streptavidin Europium based FRET assay Homo sapiens 34 single protein format Scientific Literature 8. ALA4705226 A AUC (0 to infinity) in Wistar Han rat at 1 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 9. ALA4705227 A AUC (0 to X) in Wistar Han rat at 1 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 10. ALA4705228 A Clearance in Wistar Han rat at 1 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 11. ALA4705229 A Volume of distribution at steady state in Wistar Han rat at 1 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA4705230 A Half life in Wistar Han rat at 1 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 2 organism-based format Scientific Literature 13. ALA4705231 A Protein binding in Wistar Han rat plasma Rattus norvegicus 2 cell-free format Scientific Literature 14. ALA4705232 A AUC (0 to infinity) in cynomolgus monkey at 0.5 mg/kg, iv by LC-MS/MS analysis Macaca fascicularis 1 organism-based format Scientific Literature 15. ALA4705233 A AUC (0 to X) in cynomolgus monkey at 0.5 mg/kg, iv by LC-MS/MS analysis Macaca fascicularis 1 organism-based format Scientific Literature 16. ALA4705234 A Clearance in cynomolgus monkey at 0.5 mg/kg, iv by LC-MS/MS analysis Macaca fascicularis 1 organism-based format Scientific Literature 17. ALA4705235 A Volume of distribution at steady state in cynomolgus monkey at 0.5 mg/kg, iv by LC-MS/MS analysis Macaca fascicularis 1 organism-based format Scientific Literature 18. ALA4705236 A Half life in cynomolgus monkey at 0.5 mg/kg, iv by LC-MS/MS analysis Macaca fascicularis 1 organism-based format Scientific Literature 19. ALA4705237 A Protein binding in cynomolgus monkey plasma Macaca fascicularis 1 cell-free format Scientific Literature 20. ALA5035794 B Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assay Homo sapiens 17 single protein format Scientific Literature