# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701303 | Binding | Inhibition of N-terminal FLAG-tagged and C-terminal strep-tagged human PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 1 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay | Homo sapiens | 10 | ALA4699460 | cell-based format | Scientific Literature | |
2. | ALA4701304 | Binding | Inhibition of N-terminal FLAG-tagged and C-terminal strep-tagged human PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 10 | ALA4699460 | cell-based format | Scientific Literature | |
3. | ALA4701305 | Binding | Inhibition of N-terminal His-GST tagged human PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 1 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 10 | ALA4699460 | cell-based format | Scientific Literature | |
4. | ALA4701316 | Binding | Inhibition of N-terminal His-GST tagged human PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 3 | ALA4699460 | cell-based format | Scientific Literature |