# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4736564 | Binding | Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mins by biomol green reagent based assay | Homo sapiens | 28 | ALA4732155 | assay format | Scientific Literature | |
2. | ALA4736565 | Binding | Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 mins by luciferase reporter gene assay | Homo sapiens | 28 | ALA4732155 | cell-based format | Scientific Literature | |
3. | ALA4736566 | Functional | Inhibition of proteasomal turnover of p97-independent ODD-luciferase reporter substrate in human HeLa cells incubated for 120 mins by luciferase reporter gene assay | Homo sapiens | 28 | ALA4732155 | cell-based format | Scientific Literature | |
4. | ALA4736571 | Binding | Inhibition of yeast Cdc48 T532C mutant assessed as reduction in ATPase activity measured after 60 mins by biomol green reagent based assay | Saccharomyces cerevisiae | 12 | ALA4732155 | assay format | Scientific Literature |