# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4681089 | Functional | Agonist activity at human 5-HT2C receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
2. | ALA4681090 | Functional | Agonist activity at human 5-HT2C receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay relative to 5-HT | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
3. | ALA4681091 | Functional | Agonist activity at human 5-HT2C receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log (Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
4. | ALA4681093 | Functional | Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
5. | ALA4681094 | Functional | Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay relative to 5-HT | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
6. | ALA4681095 | Functional | Agonist activity at human 5-HT2B receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log(Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
7. | ALA4681097 | Functional | Agonist activity at human 5-HT2A receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
8. | ALA4681098 | Functional | Agonist activity at human 5-HT2A receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay relative to 5-HT | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
9. | ALA4681099 | Functional | Agonist activity at human 5-HT2A receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log(Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 44 | ALA4680082 | cell-based format | Scientific Literature | |
10. | ALA4681101 | Functional | Agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
11. | ALA4681102 | Functional | Agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay relative to 5-HT | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
12. | ALA4681103 | Functional | Agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux by measuring log (Emax/EC50) incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
13. | ALA4681104 | Binding | Agonist activity at human 5-HT2C INI receptor expressed in human HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 20 hrs by Tango assay | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
14. | ALA4681105 | Binding | Agonist activity at human 5-HT2C INI receptor expressed in human HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 20 hrs by Tango assay relative to 5HT | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
15. | ALA4681106 | Binding | Agonist activity at human 5-HT2C INI receptor expressed in human HEK293 cells assessed as induction of beta-arrestin-2 recruitment by measuring log (Emax/EC50) incubated for 20 hrs by Tango assay relative to 5HT | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
16. | ALA4681107 | Functional | Bias factor, ratio of log(Emax/EC50) of lorcaserin to test compound for agonist activity at human 5-HT2C INI receptor expressed in human Flp-In-293 cells assessed as induction of calcium flux incubated for 1 hr by Fluo-4 direct dye based FLIPR assay | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
17. | ALA4681108 | Binding | Bias factor, ratio of log(Emax/EC50) of lorcaserin to test compound for agonist activity at human 5-HT2C INI receptor expressed in human HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 20 hrs by Tango assay | Homo sapiens | 9 | ALA4680082 | cell-based format | Scientific Literature | |
18. | ALA4681109 | Binding | Agonist activity at MT1 (unknown origin) expressed in HEK293T cells incubated for 15 mins by melatonin Gi/o-mediated cAMP inhibition GloSensor assay | Homo sapiens | 6 | ALA4680082 | cell-based format | Scientific Literature | |
19. | ALA4681110 | Functional | Agonist activity at MT2(unknown origin) expressed in HEK293T cells incubated for 15 mins by melatonin Gi/o-mediated cAMP inhibition GloSensor assay | Homo sapiens | 6 | ALA4680082 | cell-based format | Scientific Literature |