# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4711021 | B | Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatal membranes incubated for 120 mins by microbeta scintillation counting method | Rattus norvegicus | 43 | cell membrane format | Scientific Literature | ||
2. | ALA4711022 | B | Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting method | Rattus norvegicus | 43 | cell membrane format | Scientific Literature | ||
3. | ALA4711023 | B | Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | Cavia porcellus | 43 | cell membrane format | Scientific Literature | ||
4. | ALA4711024 | B | Selectivity ratio of Ki for SERT in Sprague-Dawley rat midbrain membranes to Ki for DAT in Sprague-Dawley rat striatum membranes | Rattus norvegicus | 43 | assay format | Scientific Literature | ||
5. | ALA4711025 | B | Selectivity ratio of Ki for sigma 1 receptor in guinea pig brain cortex membranes to Ki for DAT in Sprague-Dawley rat striatum membranes | 42 | cell membrane format | Scientific Literature | |||
6. | ALA4711026 | B | Displacement of [3H]-N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | cell membrane format | Scientific Literature | ||
7. | ALA4711027 | B | Displacement of [3H]-N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | cell membrane format | Scientific Literature | ||
8. | ALA4711028 | B | Displacement of [3H]-N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | cell membrane format | Scientific Literature | ||
9. | ALA4711029 | B | Displacement of [3H]-Nisoxetine from NET in Sprague-Dawley rat frontal cortex membrane after 180 mins by microbeta scintillation counting method | Rattus norvegicus | 15 | cell membrane format | Scientific Literature | ||
10. | ALA4711030 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 10 uM incubated for 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Rattus norvegicus | 9 | microsome format | Scientific Literature | ||
11. | ALA4711032 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 10 uM in presence of NADPH regenerating system by LC-MS/MS analysis | Rattus norvegicus | 9 | microsome format | Scientific Literature | ||
12. | ALA4711033 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 10 uM incubated for 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
13. | ALA4711034 | T | Toxicity in Swiss Webster mouse assessed as stimulation of ambulatory activity by measuring total distance travelled at 1 to 30 mg/kg, ip measured every 5 mins for 2 hrs | Mus musculus | 3 | organism-based format | Scientific Literature |