# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4670665 | Binding | Agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing Gbeta1-RGFP protein assessed as induction of G protein activation incubated for 15 mins by BRET assay | Homo sapiens | 49 | ALA4665800 | cell-based format | Scientific Literature | |
2. | ALA4670666 | Binding | Potency index, ratio of EC50 for N/OFQ(1-13)-NH2 to EC50 for test compound for agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing Gbeta1-RGFP protein assessed as induction of G protein activation incubated for 15 mins by BRET assay | Homo sapiens | 56 | ALA4665800 | cell-based format | Scientific Literature | |
3. | ALA4670667 | Binding | Agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-arrestin2 activation incubated for 15 mins by BRET assay | Homo sapiens | 46 | ALA4665800 | cell-based format | Scientific Literature | |
4. | ALA4670668 | Binding | Potency index, ratio of EC50 for N/OFQ(1-13)-NH2 to EC50 for test compound for agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-arrestin2 activation incubated for 15 mins by BRET assay | Homo sapiens | 54 | ALA4665800 | cell-based format | Scientific Literature | |
5. | ALA4670669 | Binding | Bias factor, selectivity for agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-arrestin2 activation to agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing Gbeta1-RGFP protein assessed as induction of G protein activation | Homo sapiens | 45 | ALA4665800 | cell-based format | Scientific Literature |