# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4734658 | Binding | Inhibition of N-terminal His-tagged human IDO1 expressed in Escherichia coli using L-Trp as substrate by UV absorbance method | Homo sapiens | 1 | ALA4732103 | assay format | Scientific Literature | |
2. | ALA4734659 | Binding | Inhibition of N-terminal 6His-tagged recombinant human IDO2 (15 to 420 residues) expressed in Escherichia coli using L-Trp as substrate by UV absorbance method | Homo sapiens | 1 | ALA4732103 | assay format | Scientific Literature | |
3. | ALA4734660 | Binding | Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-Trp as substrate incubated for 48 hrs by Ehrlich reagent based assay | Homo sapiens | 1 | ALA4732103 | tissue-based format | Scientific Literature | |
4. | ALA4734661 | Binding | Inhibition of recombinant human N-terminal His-tagged TDO (2 to 406 residues) expressed in Escherichia coli using L-Trp as substrate by UV absorbance method | Homo sapiens | 1 | ALA4732103 | assay format | Scientific Literature | |
5. | ALA5216266 | Binding | Inhibition of human recombinant N-terminal His tagged IDO1 expressed in Escherichia coli using L-Trp as substrate by measuring amount of N-formylkynurenine formed by UV based method | Homo sapiens | 1 | ALA5214925 | assay format | Scientific Literature | |
6. | ALA5216267 | Binding | Inhibition of human TDO by UV based assay | Homo sapiens | 1 | ALA5214925 | single protein format | Scientific Literature | |
7. | ALA5216269 | Functional | Antitumor activity against Lewis lung carcinoma cell in C57BL/6 mouse assessed as decrease in tumor volume at 60 mg/kg relative to control | Mus musculus | 1 | ALA5214925 | organism-based format | Scientific Literature | |
8. | ALA5235150 | Binding | Inhibition of IDO1 in human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by absorbance based analysis | Homo sapiens | 1 | ALA5233260 | cell-based format | Scientific Literature | |
9. | ALA5235151 | Binding | Inhibition of human N-terminal his-tagged IDO1 expressed in Escherichia coli using L-tryptophan as substrate by UV absorption based analysis | Homo sapiens | 1 | ALA5233260 | assay format | Scientific Literature | |
10. | ALA5236775 | Binding | Inhibition of IDO1 (unknown origin) | Homo sapiens | 8 | ALA5236544 | single protein format | Scientific Literature | |
11. | ALA5236783 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 3 | ALA5236544 | cell-based format | Scientific Literature | |
12. | ALA5236789 | Binding | Inhibition of IDO2 (unknown origin) | Homo sapiens | 1 | ALA5236544 | single protein format | Scientific Literature | |
13. | ALA5236796 | Functional | Antitumor activity against human HeLa cells xenografted in mouse model assessed as reduction in tumor growth at 60 mg/kg bid relative to control | Homo sapiens | 1 | ALA5236544 | organism-based format | Scientific Literature |