# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4679621 | P | Aggregation property of compound in PBS with 0.01% Triton X-100 assessed as diameter of heterogeneous particle at 12.5 uM by dynamic light scattering analysis | 1 | ALA4673387 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4679622 | B | Binding affinity to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells assessed as inhibition of uPAR-uPA ATF protein-protein interaction up to 10 uM measured after 30 mins in presence of 0.01 to 0.1% Triton X-100 by ELISA | Homo sapiens | 1 | ALA4673387 | cell-based format | Scientific Literature | |
3. | ALA4679623 | P | Thiol reactivity in acetyl-MSTI assessed as cysteine-adduct formation at 100 uM measured after 30 mins by fluorescence assay | 7 | ALA4673387 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4679624 | B | Binding affinity to uPA ATF (unknown origin) assessed as inhibition of uPAR-uPA ATF protein-protein interaction up to 100 uM preincubated for 30 mins followed by washout and subsequent uPAR addition by ELISA | Homo sapiens | 1 | ALA4673387 | single protein format | Scientific Literature | |
5. | ALA4679625 | B | Inhibition of FAM-AID peptide binding to His-tagged Cav2.2beta subunit (unknown origin) expressed in Escherichia coli BL21 (DE3) cells at 100 uM preincubated for 15 mins followed by FAM-AID peptide addition by fluorescence polarization assay | Homo sapiens | 16 | ALA4673387 | cell-based format | Scientific Literature | |
6. | ALA4679626 | B | Inhibition of FAM-YAP (60 to 99 residue) binding to GST-fused TEAD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells at 100 uM preincubated for 15 mins followed by FAM-YAP peptide addition by fluorescence polarization assay | Homo sapiens | 16 | ALA4673387 | cell-based format | Scientific Literature | |
7. | ALA4679627 | B | Binding affinity to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells assessed as inhibition of uPAR-biotin-labeled uPA ATF protein-protein interaction by biolayer interferometry | Homo sapiens | 3 | ALA4673387 | cell-based format | Scientific Literature | |
8. | ALA4679628 | B | Binding affinity to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells assessed as inhibition of uPAR-uPA ATF protein-protein interaction measured after 30 mins by ELISA | Homo sapiens | 17 | ALA4673387 | cell-based format | Scientific Literature | |
9. | ALA4679629 | B | Inhibition of AE147-FAM peptide binding to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells preincubated for 15 min followed by AE147-FAM peptide addition by fluorescence polarization assay | Homo sapiens | 17 | ALA4673387 | cell-based format | Scientific Literature | |
10. | ALA4679630 | B | Binding affinity to NT-495-labelled recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells measured after 20 mins by microscale thermophoresis analysis | Homo sapiens | 3 | ALA4673387 | cell-based format | Scientific Literature | |
11. | ALA4679631 | B | Inhibition of biotin-labeled 8B12 binding to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells by biolayer interferometry | Homo sapiens | 2 | ALA4673387 | cell-based format | Scientific Literature | |
12. | ALA4679632 | B | Binding affinity to FAM-labelled AE147 peptide by fluorescence polarization assay | 1 | ALA4673387 | assay format | Scientific Literature | ||
13. | ALA4679633 | B | Inhibition of AE147-FAM peptide binding to recombinant soluble form urokinase-type plasminogen activator receptor (unknown origin) expressed in S2 cells preincubated for 15 min followed by AE147-FAM peptide addition by fluorescence polarization assay relative to control | Homo sapiens | 17 | ALA4673387 | cell-based format | Scientific Literature | |
14. | ALA4679634 | P | Aggregation property of compound in PBS with 0.01% Triton X-100 assessed as polydispersity at 12.5 uM by dynamic light scattering analysis | 1 | ALA4673387 | small-molecule physicochemical format | Scientific Literature |