# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4742447 | Binding | Inhibition of CDK8 in human SW-620 cells assessed as reduction in IFNgamma-induced STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 8 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
2. | ALA4742448 | Binding | Inhibition of haspin in synchronized human SW620 cells assessed as reduction in IFNgamma-induced H3T3 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 8 | ALA4742387 | tissue-based format | Patent Bioactivity Data | |
3. | ALA4742449 | Binding | Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 14 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
4. | ALA4742450 | Binding | Inhibition of haspin in human SW620 cells assessed as reduction in IFNgamma-induced H3T3 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 9 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
5. | ALA4742451 | Functional | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
6. | ALA4742452 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
7. | ALA4742453 | Functional | Antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 27 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
8. | ALA4742454 | Functional | Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 22 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
9. | ALA4742455 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of taxol by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
10. | ALA4742456 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of ABT-751 by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
11. | ALA4742457 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of Ali-sertib by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
12. | ALA4742458 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of Elesclomol by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
13. | ALA4742459 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of Crizotinib by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
14. | ALA4742460 | Functional | Synergistic antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by measuring combination index in presence of oxaliplatin by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
15. | ALA4742461 | Functional | Synergistic antiproliferative activity against human HCT-116 cells assessed as reduction in cell proliferation by measuring combination index in presence of taxol by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
16. | ALA4742462 | Functional | Synergistic antiproliferative activity against human HCT-116 cells assessed as reduction in cell proliferation by measuring combination index in presence of Ali-sertib by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
17. | ALA4742463 | Functional | Synergistic antiproliferative activity against human HCT-116 cells assessed as reduction in cell proliferation by measuring combination index in presence of crizotinib by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
18. | ALA4742464 | Functional | Synergistic antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation by measuring combination index in presence of Elesclomol by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
19. | ALA4742465 | Functional | Synergistic antiproliferative activity against human A549 cells assessed as reduction in cell proliferation by measuring combination index in presence of Elesclomol by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
20. | ALA4742466 | Functional | Synergistic antiproliferative activity against human SK-MEL19 cells assessed as reduction in cell proliferation by measuring combination index in presence of Crizotinib by MTT assay | Homo sapiens | 1 | ALA4742387 | cell-based format | Patent Bioactivity Data |