# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4733372 | B | Inhibition of recombinant rat SK3 expressed in HEK293T cells assessed as reduction in channel current at 10 uM and holding potential at 0 mV by whole cell patch clamp method relative to control | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
2. | ALA4733373 | F | Inhibition of cell migration in human MDA-MB-435 cells expressing SK3 channel at 1 uM measured after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4733374 | F | Inhibition of cell migration in human MDA-MB-435 cells expressing SK3 channel at 0.3 uM measured after 24 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4733375 | F | Inhibition of cell migration in human MDA-MB-435 cells at 1 uM measured after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4733376 | A | Cytotoxicity against human MDA-MB-435 cells at 1 uM incubated for 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4733377 | A | Drug uptake in plasma membrane of human MDA-MB-231 cells at 1 uM measured after 45 mins by fluorescence imaging analysis | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
7. | ALA4733378 | A | Drug uptake in human MDA-MB-231 cells at 1 uM after 2 hrs by fluorescence imaging analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4733379 | B | Inhibition of SK3 (unknown origin) assessed as reduction in SK3 expression in presence of proteinase K | Homo sapiens | 2 | assay format | Scientific Literature | ||
9. | ALA4733380 | P | Fluorescence property of compound in egg-PC based liposomes assessed as liposomal integration at 0.2 uM added before liposome formation by fluorescence spectra analysis | 3 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4733381 | P | Fluorescence property of compound in preformed egg-PC based liposomes assessed as liposomal integration at 0.2 uM by fluorescence spectra analysis | 3 | small-molecule physicochemical format | Scientific Literature |