# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700075 | F | Antitrypanosomal activity against blood stream form of Trypanosoma brucei brucei 427 assessed as parasite growth inhibition incubated for 48 hrs by alamar blue dye based assay | Trypanosoma brucei brucei | 44 | ALA4699413 | organism-based format | Scientific Literature | |
2. | ALA4700076 | A | Cytotoxicity against human WIL2-NS cells assessed as reduction in cell viability after 48 hrs by alamar blue dye based assay | Homo sapiens | 43 | ALA4699413 | cell-based format | Scientific Literature | |
3. | ALA4700077 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by alamar blue dye based assay | Homo sapiens | 43 | ALA4699413 | cell-based format | Scientific Literature | |
4. | ALA4700078 | A | Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISA | Homo sapiens | 12 | ALA4699413 | cell-based format | Scientific Literature | |
5. | ALA4700079 | T | Selectivity index, ratio of EC50 for inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells to EC50 for antitrypanosomal activity against blood stream form of Trypanosoma brucei brucei 427 | 11 | ALA4699413 | cell-based format | Scientific Literature | ||
6. | ALA4700080 | A | Ratio of drug level in brain to plasma in Swiss Webster mouse at 5 mg/kg, ip measured after 60 mins by LC-MS analysis | Mus musculus | 11 | ALA4699413 | organism-based format | Scientific Literature |