# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4773127 | F | Cytotoxicity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 36 | ALA4765407 | cell-based format | Scientific Literature | |
2. | ALA4773132 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 27 | ALA4765407 | cell-based format | Scientific Literature | |
3. | ALA4773134 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 13 | ALA4765407 | cell-based format | Scientific Literature | |
4. | ALA4773135 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 19 | ALA4765407 | cell-based format | Scientific Literature | |
5. | ALA4773136 | F | Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 31 | ALA4765407 | cell-based format | Scientific Literature | |
6. | ALA4773137 | F | Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 25 | ALA4765407 | cell-based format | Scientific Literature | |
7. | ALA4773138 | F | Cytotoxicity against human BXPC-3 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 14 | ALA4765407 | cell-based format | Scientific Literature | |
8. | ALA4773139 | F | Cytotoxicity against human ASPC1 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 19 | ALA4765407 | cell-based format | Scientific Literature | |
9. | ALA4773140 | F | Cytotoxicity against human Capan-2 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 9 | ALA4765407 | cell-based format | Scientific Literature | |
10. | ALA4773151 | F | Antitumour activity against Walker 256 adenocarcinoma cells implanted in Wistar rat assessed as increase in animal survival rate by measuring T/C ratio at 1.25 mg/kg, ip qd for 3 days administered on day 3,4,5 after tumor cell transplantation | Rattus norvegicus | 6 | ALA4765407 | organism-based format | Scientific Literature | |
11. | ALA4773207 | F | Antitumour activity against human PANC-1 cells xenografted in Crl:Nu-Foxnl nu mouse assessed as inhibition of tumour growth at total effective dose of 16 mg/kg, iv measured on day 38 | Homo sapiens | 1 | ALA4765407 | organism-based format | Scientific Literature | |
12. | ALA4773208 | F | Antitumour activity against human PANC-1 cells xenografted in Crl:Nu-Foxnl nu mouse assessed as inhibition of tumour growth at total effective dose of 16 mg/kg, iv measured on day 60 | Homo sapiens | 1 | ALA4765407 | organism-based format | Scientific Literature | |
13. | ALA4773244 | B | Stabilization of 5'-FAM/3'-TAMRA labeled c-Myc promoter G4 quadruplex DNA FPu18 (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature | |
14. | ALA4773245 | B | Stabilization of 5'-FAM/3'-TAMRA labeled telomeric G4 quadruplex DNA F21T (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature | |
15. | ALA4773246 | B | Stabilization of 5'-FAM/3'-TAMRA labeled K-Ras G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature | |
16. | ALA4773247 | B | Stabilization of ds 5'-FAM-d(TATAGCTATA-HEG-TATAGCTATA)-TAMRA-3' (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Homo sapiens | 18 | ALA4765407 | assay format | Scientific Literature |