# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4769705 | B | Inhibition of ALK5 (unknown origin) measured after 120 mins of incubation by ADP-Glo kinase assay | Homo sapiens | 28 | ALA4765311 | single protein format | Scientific Literature | |
2. | ALA4769707 | B | Inhibition of TGF-beta type 1 receptor in mouse NIH3T3 cells expressing Luc-Smad 2/3 measured after 24 hrs incubation by cell based Bright-Glo Luciferase assay | Mus musculus | 28 | ALA4765311 | cell-based format | Scientific Literature | |
3. | ALA4769708 | A | Half life in BALB/c mouse at 1 mg/kg, iv measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
4. | ALA4769709 | A | Clearance in BALB/c mouse at 1 mg/kg, iv measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
5. | ALA4769710 | A | Volume of distribution at steady state in BALB/c mouse at 1 mg/kg, iv measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
6. | ALA4769711 | A | AUC (0 to 24 hrs) in BALB/c mouse at 1 mg/kg, iv measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
7. | ALA4769712 | A | Half life in BALB/c mouse at 10 mg/kg, po measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
8. | ALA4769713 | A | Cmax in BALB/c mouse at 10 mg/kg, po measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
9. | ALA4769714 | A | AUC (0 to 24 hrs) in BALB/c mouse at 10 mg/kg, po measured upto 24 hr by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature | |
10. | ALA4769715 | A | Oral bioavailability in BALB/c mouse at 10 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 8 | ALA4765311 | organism-based format | Scientific Literature |