| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4668672 | A | Cytotoxicity against mouse J774.A1 cells assessed as cell viability at 10 to 20 uM after 24 hrs by MTT assay | Mus musculus | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA4668673 | B | Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS-induced NO production at 20 uM measured after 24 hrs by Griess reagent | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4668674 | B | Inhibition of NLRP3 in mouse J774A.1 cells assessed as inhibition of LPS and nigerecin-induced IL-1beta production at 20 uM pre-stimulated with LPS for 5 hrs followed by compound treatment for 30 mins and then nigericin addition for 45 mins by ELISA | Mus musculus | 4 | cell-based format | Scientific Literature |
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