# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4742444 | B | Inhibition of kinase tracer 236 binding to full-length His-tagged recombinant human CDK8/cyclin C incubated for 60 mins by FRET based LanthaScreen Eu-Kinase binding assay | Homo sapiens | 32 | ALA4742387 | protein complex format | Patent Bioactivity Data | |
2. | ALA4742445 | B | Inhibition of GST-tagged recombinant human haspin kinase domain incubated for 60 mins by ADP-Glo luminescent kinase assay | Homo sapiens | 32 | ALA4742387 | single protein format | Patent Bioactivity Data | |
3. | ALA4742446 | B | Inhibition of kinase tracer 236 binding to full-length His-tagged recombinant human CDK19/cyclin C incubated for 60 mins by FRET based LanthaScreen Eu-Kinase binding assay | Homo sapiens | 20 | ALA4742387 | protein complex format | Patent Bioactivity Data | |
4. | ALA4742449 | B | Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis | Homo sapiens | 14 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
5. | ALA4742451 | F | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
6. | ALA4742452 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 24 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
7. | ALA4742453 | F | Antiproliferative activity against human SW-620 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 27 | ALA4742387 | cell-based format | Patent Bioactivity Data | |
8. | ALA4742454 | F | Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell proliferation by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 22 | ALA4742387 | cell-based format | Patent Bioactivity Data |