# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4742640 | B | Selectivity index, ratio of inhibition of full length human MKK7 (M1 to R419 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control | Homo sapiens | 18 | ALA4742403 | assay format | Patent Bioactivity Data | |
2. | ALA4742641 | B | Inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control | Homo sapiens | 18 | ALA4742403 | assay format | Patent Bioactivity Data | |
3. | ALA4742642 | B | Selectivity index, ratio of inhibition of full length human JNK1 (M1 to Q384 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control | Homo sapiens | 18 | ALA4742403 | assay format | Patent Bioactivity Data | |
4. | ALA4742643 | B | Selectivity index, ratio of inhibition of B-raf (unknown origin) to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control | Homo sapiens | 18 | ALA4742403 | assay format | Patent Bioactivity Data | |
5. | ALA5118600 | B | Binding affinity to BRAF (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control | Homo sapiens | 30 | ALA5113505 | single protein format | Scientific Literature | |
6. | ALA5118601 | B | Binding affinity to JNK1 (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control | Homo sapiens | 29 | ALA5113505 | single protein format | Scientific Literature | |
7. | ALA5118602 | B | Binding affinity to MKK4 (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control | Homo sapiens | 30 | ALA5113505 | single protein format | Scientific Literature | |
8. | ALA5118603 | B | Binding affinity to MKK7 (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control | Homo sapiens | 30 | ALA5113505 | single protein format | Scientific Literature | |
9. | ALA5118604 | B | Binding affinity to ZAK (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control | Homo sapiens | 29 | ALA5113505 | single protein format | Scientific Literature | |
10. | ALA5118605 | F | Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM incubated for 72 hrs by Cell Titer Glo luminescent assay | Homo sapiens | 1 | ALA5113505 | cell-based format | Scientific Literature |