# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4719643 | F | Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
2. | ALA4719644 | A | Half life in 25% human serum by RP-HPLC analysis | Homo sapiens | 15 | cell-free format | Scientific Literature | ||
3. | ALA4719645 | F | Agonist activity at human U-IIR expressed in HEK293-A cells assessed as delta F/F0 ratio by Fluo4-AM dye based intracellular calcium mobilization assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
4. | ALA4719646 | B | Displacement of [125I-Tyr9]-U-II from human U-IIR expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand binding assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
5. | ALA4719652 | B | Agonist activity at U-IIR in pig aorta VSMC assessed as increase of ERK1/2 phosphorylation at 500 nM incubated for 15 mins by Western blot analysis relative to control | Sus scrofa | 2 | tissue-based format | Scientific Literature | ||
6. | ALA4719653 | B | Agonist activity at U-IIR in pig aorta VSMC assessed as increase of ERK1/2 phosphorylation at 5 nM incubated for 15 mins by Western blot analysis relative to control | Sus scrofa | 2 | tissue-based format | Scientific Literature | ||
7. | ALA4719656 | B | Agonist activity at U-IIR in pig aorta VSMC assessed as increase of ERK1/2 phosphorylation incubated for 15 mins by Western blot analysis relative to control | Sus scrofa | 2 | tissue-based format | Scientific Literature |