# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4770179 | Binding | Disruption of cell membrane integrity in Staphylococcus aureus at 2 uM irradiated with 6J/cm2 light followed by compound exposure for 10 mins by FL-4L/propidium iodide Live/dead staining based laser confocal microscopic analysis | Staphylococcus aureus | 2 | ALA4765326 | subcellular format | Scientific Literature | |
2. | ALA4770180 | Functional | Induction of singlet oxygen generation in DPBF solution assessed as singlet oxygen quantum yield irradiated with 80 mW/cm2 light by DPBF-based assay | 12 | ALA4765326 | assay format | Scientific Literature | ||
3. | ALA4770181 | Physicochemical | Octanol-water partition coefficient, logP of compound incubated for 24 hrs under shaking condition | 14 | ALA4765326 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4770182 | Functional | Photodynamic antibacterial activity against Staphylococcus aureus assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
5. | ALA4770183 | Functional | Photodynamic antibacterial activity against Escherichia coli assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Escherichia coli | 12 | ALA4765326 | organism-based format | Scientific Literature | |
6. | ALA4770184 | Functional | Photodynamic antifungal activity against Candida albicans assessed as fungal eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Candida albicans | 12 | ALA4765326 | organism-based format | Scientific Literature | |
7. | ALA4770185 | Functional | Photodynamic antibacterial activity against methicillin resistant Staphylococcus aureus assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
8. | ALA4770194 | Binding | Binding affinity to Staphylococcus aureus cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Staphylococcus aureus | 3 | ALA4765326 | assay format | Scientific Literature | |
9. | ALA4770195 | Binding | Binding affinity to Escherichia coli cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Escherichia coli | 3 | ALA4765326 | assay format | Scientific Literature | |
10. | ALA4770196 | Binding | Binding affinity to Candida albicans cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Candida albicans | 3 | ALA4765326 | assay format | Scientific Literature | |
11. | ALA4770198 | Binding | Binding affinity to Staphylococcus aureus cell wall at 50 uM preincubated with 12.5 to 50 mM Ca2+ for 30 mins followed by incubation with compound for 30 mins | Staphylococcus aureus | 3 | ALA4765326 | assay format | Scientific Literature | |
12. | ALA4770199 | Binding | Binding affinity to Escherichia coli cell wall at 50 uM preincubated with 12.5 to 50 mM Ca2+ for 30 mins followed by incubation with compound for 30 mins | Escherichia coli | 3 | ALA4765326 | assay format | Scientific Literature | |
13. | ALA4770200 | Binding | Binding affinity to Candida albicans cell wall at 50 uM preincubated with 12.5 to 50 mM Ca2+ for 30 mins followed by incubation with compound for 30 mins | Candida albicans | 3 | ALA4765326 | assay format | Scientific Literature | |
14. | ALA4770201 | Binding | Disruption of cell membrane integrity in Escherichia coli at 2 uM irradiated with 6J/cm2 light followed by compound exposure for 10 mins by FL-4L/propidium iodide Live/dead staining based laser confocal microscopic analysis | Escherichia coli | 2 | ALA4765326 | subcellular format | Scientific Literature | |
15. | ALA4770202 | Binding | Disruption of cell membrane integrity in Candida albicans at 2 uM irradiated with 6J/cm2 light followed by compound exposure for 10 mins by FL-4L/propidium iodide Live/dead staining based laser confocal microscopic analysis | Candida albicans | 2 | ALA4765326 | assay format | Scientific Literature | |
16. | ALA4770205 | Functional | Antibacterial activity against Staphylococcus aureus up to 80 uM by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
17. | ALA4770206 | Functional | Antibacterial activity against Escherichia coli up to 80 uM by broth microdilution method | Escherichia coli | 12 | ALA4765326 | organism-based format | Scientific Literature | |
18. | ALA4770207 | Functional | Antifungal activity against Candida albicans up to 80 uM by broth microdilution method | Candida albicans | 12 | ALA4765326 | organism-based format | Scientific Literature | |
19. | ALA4770208 | Functional | Antibacterial activity against methicillin resistant Staphylococcus aureus up to 80 uM by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
20. | ALA4770213 | Binding | Binding affinity to Staphylococcus aureus cell membrane assessed as reduction in zeta potential by zetasizer-based analysis | Staphylococcus aureus | 3 | ALA4765326 | subcellular format | Scientific Literature |