#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4682224	Binding	Inhibition of recombinant full-length human FLAG-tagged ATM assessed as reduction in p53 S15 phosphorylation incubated for 30 mins by ELISA	Homo sapiens	41	ALA4680114	single protein format	Scientific Literature
2.	ALA4682225	Binding	Inhibition of ATM in human MCF7 cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 1 hr by ICW assay	Homo sapiens	41	ALA4680114	cell-based format	Scientific Literature
3.	ALA4682226	Physicochemical	Kinetic solubility in pH 7.4 PBS buffer by LC-UV assay		41	ALA4680114	small-molecule physicochemical format	Scientific Literature
4.	ALA4682227	ADME	Efflux ratio in MDCK-MDR1 cells incubated for 1 hr by LC-MS/MS analysis	Canis lupus familiaris	41	ALA4680114	cell-based format	Scientific Literature
5.	ALA4682228	ADME	Apparent permeability in MDCK-MDR1 cells incubated for 1 hr by LC-MS/MS analysis	Canis lupus familiaris	41	ALA4680114	cell-based format	Scientific Literature
6.	ALA4682229	ADME	Intrinsic clearance in mouse liver microsomes at 1 uM in presence of NADPH incubated up to 40 mins by LC-MS/MS analysis	Mus musculus	34	ALA4680114	microsome format	Scientific Literature
7.	ALA4682230	Binding	Binding affinity to human Vps34 expressed in mammalian expression system	Homo sapiens	4	ALA4680114	assay format	Scientific Literature
8.	ALA4682231	ADME	Intrinsic clearance in mouse hepatocytes	Mus musculus	26	ALA4680114	cell-based format	Scientific Literature
9.	ALA4682232	Binding	Inhibition of ATR in human HeLa cells incubated for 4 hrs	Homo sapiens	7	ALA4680114	cell-based format	Scientific Literature
10.	ALA4682233	Binding	Inhibition of recombinant full-length human VPS34 incubated for 60 mins by ADP-Glo kinase assay	Homo sapiens	7	ALA4680114	single protein format	Scientific Literature
11.	ALA4682234	Binding	Inhibition of DNA-PK isolated from human HeLa cells assessed as reduction in p53 Ser15 phosphorylation by HTRF assay	Homo sapiens	7	ALA4680114	assay format	Scientific Literature
12.	ALA4682235	ADME	AUC/dose in C57BL/6J mouse plasma at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
13.	ALA4682236	ADME	AUC/dose in C57BL/6J mouse brain at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
14.	ALA4682237	ADME	Plasma clearance in C57BL/6J mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
15.	ALA4682238	ADME	Volume of distribution at steady state in C57BL/6J mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
16.	ALA4682239	ADME	Half life in C57BL/6J mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
17.	ALA4682240	ADME	Ratio of AUC/dose in brain to plasma of C57BL/6J mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
18.	ALA4682241	ADME	Unbound brain-to-plasma concentration ratio in C57BL/6J mouse at 3 mg/kg, iv administered as single dose by LC-MS/MS analysis	Mus musculus	8	ALA4680114	organism-based format	Scientific Literature
19.	ALA4682242	ADME	AUC/dose in C57BL/6J mouse plasma at 10 mg/kg, po by LC-MS/MS analysis	Mus musculus	1	ALA4680114	organism-based format	Scientific Literature
20.	ALA4682243	ADME	Oral bioavailability in C57BL/6J mouse plasma at 10 mg/kg by LC-MS/MS analysis	Mus musculus	1	ALA4680114	organism-based format	Scientific Literature