# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700038 | Binding | Binding affinity to EPHA3 (unknown origin) assessed as increase in change in melting temperature by differential scanning fluorimetric analysis | Homo sapiens | 2 | ALA4699412 | single protein format | Scientific Literature | |
2. | ALA4700039 | Binding | Inhibition of full-length human EPHB4 expressed in MEF cells assessed as autophosphorylation by sandwitch-ELISA | Homo sapiens | 2 | ALA4699412 | cell-based format | Scientific Literature | |
3. | ALA4700040 | Functional | Growth inhibition of human SU-DHL-2 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
4. | ALA4700041 | Functional | Growth inhibition of human MAVER-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | cell-based format | Scientific Literature | |
5. | ALA4700043 | Binding | Inhibition of wild-type human ABL2 (A248 to G542 residues) expressed in bacterial expression system by Kinomescan method | Homo sapiens | 2 | ALA4699412 | assay format | Scientific Literature | |
6. | ALA4700060 | Binding | Inhibition of wild-type human partial length LYN (C219 to Q511 residues) expressed in bacterial expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4699412 | assay format | Scientific Literature | |
7. | ALA4700061 | Binding | Inhibition of wild-type human partial length YES (T257 to L543 residues) expressed in bacterial expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4699412 | assay format | Scientific Literature | |
8. | ALA4700062 | Binding | Inhibition of wild-type human full length BTK (M1 to S659 residues) expressed in mammalian expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4699412 | assay format | Scientific Literature | |
9. | ALA4700063 | Binding | Inhibition of wild-type human full length CSK (M1 to L450 residues) expressed in bacterial expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4699412 | assay format | Scientific Literature | |
10. | ALA4700064 | Functional | Growth inhibition of human Jeko-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | cell-based format | Scientific Literature | |
11. | ALA4700065 | Functional | Growth inhibition of human MEC-1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
12. | ALA4700066 | Functional | Growth inhibition of human PCL12 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
13. | ALA4700067 | Functional | Growth inhibition of human Ri1 cells incubated for 72 hrs | Homo sapiens | 3 | ALA4699412 | tissue-based format | Scientific Literature | |
14. | ALA4700068 | Toxicity | Toxicity in NOD-SCID nude mouse xenografted with human Ri1 cells assessed as swelling surrounding the area of injection at 100 mg/kg, ip | Mus musculus | 1 | ALA4699412 | organism-based format | Scientific Literature | |
15. | ALA4700069 | Toxicity | Toxicity in NOD-SCID nude mouse xenografted with human Ri1 cells assessed as body weight loss at 100 mg/kg, ip | Mus musculus | 1 | ALA4699412 | organism-based format | Scientific Literature | |
16. | ALA4700072 | Functional | Antiangiogenic activity against HUVEC cells assessed as reduction in tube formation incubated for 15 hrs by matrigel-based assay relative to control | Homo sapiens | 1 | ALA4699412 | cell-based format | Scientific Literature | |
17. | ALA4700073 | Functional | Antiangiogenic activity against HUVEC cells assessed as reduction in total branching points incubated for 15 hrs by matrigel-based assay relative to control | Homo sapiens | 1 | ALA4699412 | cell-based format | Scientific Literature | |
18. | ALA4700074 | Functional | Antiangiogenic activity against HUVEC cells assessed as reduction in total loops incubated for 15 hrs by matrigel-based assay relative to control | Homo sapiens | 1 | ALA4699412 | cell-based format | Scientific Literature |