| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4728080 | B | Inhibition of recombinant full length USP7 (unknown origin) using di-ubiquitin as substrate by fluorescence based assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 2. | ALA4728081 | P | Aqueous solubility of compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4728082 | B | Allosteric binding affinity to USP7 catalytic domain (unknown origin) at His403, Gln351, Leu304, Ser353, Met328, Trp285 and Gly284 residues at 1.12 mM by NMR-15N-1H TROSY spectral titration analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4728083 | B | Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Gln405, Gly313 and Gln237 residues at 1.12 mM by NMR-15N-1H TROSY spectral titration analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4728084 | B | Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328, Trp285, Gly284, Gln405 and Gly313 residues by NMR-15N-1H TROSY spectral titration analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4728085 | B | Allosteric binding affinity to USP7 catalytic domain (unknown origin) at Met328 residues by NMR-15N-1H TROSY spectral titration analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4728086 | B | Binding affinity to USP7 (unknown origin) by T2 relaxation experiment based analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4728087 | B | Binding affinity to USP7 (unknown origin) by 1H-NMR-STD analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4728088 | B | Binding affinity to USP7 (unknown origin) by 1H-1H-NOESY experiment based analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4728089 | B | Inhibition of USP47 (unknown origin) | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 11. | ALA4728090 | B | Inhibition of USP1 (unknown origin) | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 12. | ALA4728091 | B | Inhibition of USP14 (unknown origin) | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 13. | ALA4728092 | B | Selectivity index, ratio of IC50 for USP47 (unknown origin) to IC50 for recombinant full length USP7 (unknown origin) using di-ubiquitin as substrate by fluorescence based assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 14. | ALA4728093 | B | Selectivity index, ratio of IC50 for USP1 (unknown origin) to IC50 for recombinant full length USP7 (unknown origin) using di-ubiquitin as substrate by fluorescence based assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 15. | ALA4728094 | B | Selectivity index, ratio of IC50 for USP14 (unknown origin) to IC50 for recombinant full length USP7 (unknown origin) using di-ubiquitin as substrate by fluorescence based assay | Homo sapiens | 13 | assay format | Scientific Literature |
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