# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4687993 | F | Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 45 | ALA4680289 | cell-based format | Scientific Literature | |
2. | ALA4687994 | B | Inhibition of porcine brain tubulin polymerization assessed as reduction in tubulin assembly at 37 degreeC measured after 40 mins in presence of GTP by turbidimetric analysis | Sus scrofa | 45 | ALA4680289 | tissue-based format | Scientific Literature | |
3. | ALA4687995 | B | Inhibition of N,N'-Ethylenebis(iodoacetamide) binding to beta-tubulin colchicine binding site in human K562 cells assessed as reduction in EBI/beta-tubulin adduct formation at 1 to 10 uM preincubated for 2.5 hrs followed by EBI addition and measured after 1.5 hrs by Western blot analysis | Homo sapiens | 2 | ALA4680289 | cell-based format | Scientific Literature | |
4. | ALA4687997 | F | Cell cycle arrest in human K562 cells assessed as increase in cell accumulation at G2/M phase at < 30 nM measured after 18 hrs by propidium iodide/RNase FACSCalibur staining based flow cytometry | Homo sapiens | 2 | ALA4680289 | cell-based format | Scientific Literature | |
5. | ALA4687998 | F | Cell cycle arrest in human K562 cells assessed as increase in cell accumulation at G2/M phase measured after 18 hrs by propidium iodide/RNase FACSCalibur staining based flow cytometry | Homo sapiens | 3 | ALA4680289 | cell-based format | Scientific Literature | |
6. | ALA4688038 | F | Antiproliferative activity against human SK-N-AS cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
7. | ALA4688039 | A | Cytotoxicity against human IMR-90 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
8. | ALA4688040 | F | Antiproliferative activity against human BXPC-3 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
9. | ALA4688041 | F | Antiproliferative activity against human MG-63 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
10. | ALA4688042 | F | Antiproliferative activity against human HT-1080 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
11. | ALA4688043 | F | Antiproliferative activity against human 5637 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
12. | ALA4688044 | F | Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
13. | ALA4688045 | F | Antiproliferative activity against human PANC-1 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
14. | ALA4688046 | F | Antiproliferative activity against human RDES cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
15. | ALA4688047 | F | Antiproliferative activity against human Ramos cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
16. | ALA4688048 | F | Antiproliferative activity against human DU-145 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
17. | ALA4688049 | F | Antiproliferative activity against human L-363 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
18. | ALA4688050 | F | Antiproliferative activity against human MV4-11 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
19. | ALA4688051 | F | Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature | |
20. | ALA4688052 | F | Antiproliferative activity against human SNB-75 cells assessed as cell growth inhibition measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA4680289 | cell-based format | Scientific Literature |