| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4730481 | T | Toxicity in human HepG2 cells assessed as cell survival at <30 uM incubated for 72 hrs by CellTiter-Glo assay | Homo sapiens | 5 | ALA4725415 | cell-based format | Scientific Literature | |
| 2. | ALA4730486 | F | Induction of wound closure in human HaCaT cells at 1 uM measured up to 96 hrs by light microscopy based wound healing assay relative to control | Homo sapiens | 2 | ALA4725415 | cell-based format | Scientific Literature | |
| 3. | ALA4730490 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay | Homo sapiens | 51 | ALA4725415 | cell-based format | Scientific Literature | |
| 4. | ALA4730491 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to CAY10583 | Homo sapiens | 40 | ALA4725415 | cell-based format | Scientific Literature | |
| 5. | ALA4730493 | B | Agonist activity at human BLT1 isoform 1 expressed in CHO-K1 cells over-expressing GNA15/16 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to control | Homo sapiens | 47 | ALA4725415 | cell-based format | Scientific Literature | |
| 6. | ALA4730497 | P | Solubility of compound in PBS buffer at pH 7.4 containing 1% dimethyl sulfoxide | 3 | ALA4725415 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4730498 | A | Metabolic stability in Sprague-Dawley rat liver microsomes assessed as parent compound remaining at 1 mM in presence of NADPH measured after 60 mins by HPLC analysis | Rattus norvegicus | 3 | ALA4725415 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!