# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4707656 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability at 5 to 80 uM after 48 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA4707658 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4707659 | F | Cytotoxicity against human A2780 cells assessed as reduction in cell viability at 5 to 80 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4707660 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 5 to 80 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4707661 | A | Cytotoxicity against human HUVEC cells assessed as reduction in cell viability at 5 to 80 uM after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4707662 | B | Protac activity at VHL/ERalpha in human MCF7 cells assessed as degradation of ERalpha protein level at 10 uM after 12 hrs by Western blot analysis | 6 | cell-based format | Scientific Literature | |||
7. | ALA4707663 | B | Protac activity at VHL/ERalpha in human MCF7 cells assessed as degradation of ERalpha protein level by Western blot analysis | 1 | cell-based format | Scientific Literature | |||
8. | ALA4707664 | B | Protac activity at VHL/ERalpha in human A2780 cells assessed as degradation of ERalpha protein level at 10 uM after 12 hrs by Western blot analysis | 1 | cell-based format | Scientific Literature | |||
9. | ALA4707665 | A | Drug uptake in human MCF7 cells at 10 uM FITC labelled form of compound after 12 hrs by flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA4707666 | A | Drug uptake in human MCF7 cells FITC labelled form of compound by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4707667 | A | Drug uptake in human MCF7 cells at 10 uM FITC labelled form of compound after 3 hrs by Hoechst 33258 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4707668 | F | Induction of apoptosis in human MCF7 cells assessed as increase in late apoptotic cells after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4707669 | F | Induction of apoptosis in human MCF7 cells assessed as increase in necrotic cells after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4707670 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at 10 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 95.4 to 97.6%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA4707671 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 10 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 0.8 to 1.6%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
16. | ALA4707672 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 10 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 0.9 to 1.9%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
17. | ALA4707673 | F | Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 10 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 0.7 to 1.1%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
18. | ALA4707674 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at 5 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 95.4 to 97.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4707675 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 5 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 0.8 to 1.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4707676 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 5 uM after 12 hrs by annexinV-FITC/PI staining based flow cytometric analysis (Rvb = 0.9 to 1.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature |