# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4674069 | Binding | Inhibition of human KHS using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control | Homo sapiens | 1 | ALA4673210 | single protein format | Scientific Literature | |
2. | ALA4674070 | Binding | Inhibition of human HGK using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4673210 | single protein format | Scientific Literature | |
3. | ALA4674071 | Binding | Inhibition of human GCK using MBP as substrate by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4673210 | single protein format | Scientific Literature | |
4. | ALA4674072 | Binding | Inhibition of human HPK1 using MBP as substrate assessed as residual activity by [gamma-33P]-ATP assay | Homo sapiens | 1 | ALA4673210 | single protein format | Scientific Literature | |
5. | ALA4674504 | ADME | Half life in rat at 0.2 mg/kg, iv | Rattus norvegicus | 4 | ALA4673210 | organism-based format | Scientific Literature | |
6. | ALA4674505 | ADME | Clearance in rat at 0.2 mg/kg, iv | Rattus norvegicus | 4 | ALA4673210 | organism-based format | Scientific Literature | |
7. | ALA4674506 | ADME | AUC in rat at 0.2 mg/kg, iv | Rattus norvegicus | 4 | ALA4673210 | organism-based format | Scientific Literature | |
8. | ALA4674507 | ADME | Efflux ratio of apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 4 | ALA4673210 | cell-based format | Scientific Literature | |
9. | ALA4674508 | ADME | Protein binding in rat plasma assessed as unbound fraction | Rattus norvegicus | 3 | ALA4673210 | cell-free format | Scientific Literature | |
10. | ALA4674509 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 7 | ALA4673210 | cell-based format | Scientific Literature | |
11. | ALA4674511 | Binding | Inhibition of GLK in human T cells assessed as reduction in PKCtheta phosphorylation by Western blot analysis | Homo sapiens | 4 | ALA4673210 | cell-based format | Scientific Literature | |
12. | ALA4674512 | Binding | Inhibition of GLK (unknown origin) transfected in human 293T cells co-transfected with GFP-fused PKCtheta assessed as reduction in PKCtheta phosphorylation by ELISA | Homo sapiens | 17 | ALA4673210 | cell-based format | Scientific Literature | |
13. | ALA4674513 | Binding | Inhibition of GLK (unknown origin) by alphascreen assay | Homo sapiens | 44 | ALA4673210 | single protein format | Scientific Literature |