# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4768523 | B | Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
2. | ALA4768524 | B | Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometry based Lineweaver-Burk plot analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA4768526 | B | Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometric assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
4. | ALA4768527 | B | Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followed by substrate addition and measured after 30 mins by fluorescence spectrophotometry based Lineweaver-Burk plot analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA4768529 | B | Chaperone activity at alpha-GalA R301G mutant in Fabry patient derived fibroblasts assessed as increase in intracellular alpha-GalA activity at 10 uM measured after 5 days by 4-methylumbelliferyl-alpha-D-glucopyranoside substrate based assay relative to control | Homo sapiens | 4 | tissue-based format | Scientific Literature |