| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4771308 | F | Antiproliferative activity against human MDA-MB-231 cells overexpressing STAT3 assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 28 | ALA4765360 | cell-based format | Scientific Literature | |
| 2. | ALA4771309 | F | Antiproliferative activity against human MDA-MB-468 cells overexpressing STAT3 assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 28 | ALA4765360 | cell-based format | Scientific Literature | |
| 3. | ALA4771310 | F | Antiproliferative activity against human HepG2 cells overexpressed STAT3 assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 27 | ALA4765360 | cell-based format | Scientific Literature | |
| 4. | ALA4771311 | B | Displacement of 5-FAM-GpYLPQTV-NH2 from His-tagged STAT3 (unknown origin) (127 to 722 residues) incubated for 30 mins followed by fluorescent peptide probe addition and measured after 1 hr by fluorescence polarization based competition binding assay | Homo sapiens | 2 | ALA4765360 | single protein format | Scientific Literature | |
| 5. | ALA4771312 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as reduction in STAT3 Y705 phosphorylation incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 6. | ALA4771313 | F | Effect on STAT3 expression in human MDA-MB-231 cells at 0.75 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 7. | ALA4771314 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as reduction in c-myc expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 8. | ALA4771315 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as reduction in Cyclin D1 expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 9. | ALA4771316 | B | Inhibition of STAT1 in human MDA-MB-231 cells assessed as reduction in STAT1 Y701 phosphorylation at 0.75 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 10. | ALA4771317 | F | Effect on STAT1 expression in human MDA-MB-231 cells at 0.75 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4765360 | cell-based format | Scientific Literature | |
| 11. | ALA4771318 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as reduction in STAT3 Y705 phosphorylation in cytoplasm at 3 uM incubated for 24 hrs by immunofluorescence staining based fluorescence microscopy | Homo sapiens | 1 | ALA4765360 | subcellular format | Scientific Literature | |
| 12. | ALA4771319 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as reduction in STAT3 Y705 phosphorylation in nucleus at 3 uM incubated for 24 hrs by immunofluorescence staining based fluorescence microscopy | Homo sapiens | 1 | ALA4765360 | subcellular format | Scientific Literature | |
| 13. | ALA4771320 | F | Induction of apoptosis in human MDA-MB-231 cells incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 14. | ALA4771321 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 1 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 93.37 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 15. | ALA4771322 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 1 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 2.69 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 16. | ALA4771323 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 1 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 3.72 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 17. | ALA4771324 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 1 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 0.23 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 18. | ALA4771325 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 2 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 93.37 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 19. | ALA4771326 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 2 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 2.69 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature | |
| 20. | ALA4771327 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 2 uM incubated for 24 hrs by annexin V-FITC and PI staining based flow cytometry analysis (Rvb = 3.72 %) | Homo sapiens | 1 | ALA4765360 | cell-based format | Scientific Literature |
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