| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4705210 | B | Inhibition of avi-tagged-biotinylated human PCSK9 interaction with His-tagged human LDLR EGFa domain by LANCE Ulight Streptavidin based TR-FRET assay | Homo sapiens | 59 | protein format | Scientific Literature | ||
| 2. | ALA4705217 | A | Enzymatic stability assessed as bovine pancreatic alpha-chymotrypsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis | Bos taurus | 15 | single protein format | Scientific Literature | ||
| 3. | ALA4705218 | A | Enzymatic stability assessed as porcine type 4 pancreatic elastase-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis | Sus scrofa | 15 | single protein format | Scientific Literature | ||
| 4. | ALA4705219 | A | Enzymatic stability assessed as porcine pepsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis | Sus scrofa | 15 | assay format | Scientific Literature | ||
| 5. | ALA4705220 | A | Enzymatic stability assessed as bovine pancreatic trypsin-mediated compound hydrolysis by measuring parent compound remaining at 100 uM incubated for 1 hr by LC-MS/MS analysis | Bos taurus | 15 | assay format | Scientific Literature | ||
| 6. | ALA4705221 | A | Half life in C57BL/6 mouse whole blood at 100 uM by LC-MS/MS analysis | Mus musculus | 15 | tissue-based format | Scientific Literature | ||
| 7. | ALA4705222 | A | Half life in cynomolgus monkey whole blood at 100 uM by LC-MS/MS analysis | Macaca fascicularis | 15 | tissue-based format | Scientific Literature | ||
| 8. | ALA4705223 | B | Inhibition of AlexaFluor647-tagged cyclic peptide binding to avi-tagged-biotinylated human PCSK9 measured after 2 hrs by Lance Streptavidin Europium based FRET assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 9. | ALA4705224 | A | Induction of mast cell degranulation in Wistar rat isolated peritoneal cells assessed as effect on histamine release measured after 30 mins | Rattus norvegicus | 14 | tissue-based format | Scientific Literature | ||
| 10. | ALA4705225 | A | Cytotoxicity against Wistar rat isolated peritoneal cells assessed as reduction in cell viability up to 60 uM measured after 30 mins | Rattus norvegicus | 14 | cell-based format | Scientific Literature |
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