# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4731851 | Functional | Antiparasitic activity against Toxoplasma gondii ME49 tachyzoites infected in human HFF-1 cells assessed as inhibition of parasitic growth preincubated for 48 hrs followed by [5,6-3H]uracil addition and measured after 24 hrs by liquid scintillation counting analysis | Toxoplasma gondii | 17 | ALA4725488 | organism-based format | Scientific Literature | |
2. | ALA4731852 | Functional | Antiparasitic activity against Toxoplasma gondii ME49 bradyzoite infected in human HFF-1 cells assessed as inhibition of parasitic growth preincubated for 48 hrs followed by [5,6-3H]uracil addition and measured after 24 hrs by liquid scintillation counting analysis | Toxoplasma gondii | 17 | ALA4725488 | organism-based format | Scientific Literature | |
3. | ALA4731853 | ADME | Cytotoxicity against HFF cells assessed as reduction in cell viability incubated for 72 hrs by Cell titer assay | Homo sapiens | 17 | ALA4725488 | cell-based format | Scientific Literature | |
4. | ALA4731854 | Toxicity | Selectivity index, ratio of CC50 for human HFF cells to EC50 for Toxoplasma gondii ME49 tachyzoites infected in human HFF cells | 17 | ALA4725488 | cell-based format | Scientific Literature | ||
5. | ALA4731865 | Toxicity | Selectivity index, ratio of CC50 for human HFF cells to EC50 for Toxoplasma gondii ME49 bradyzoite infected in human HFF cells | 17 | ALA4725488 | cell-based format | Scientific Literature |