| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4671909 | A | Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4671910 | F | Antiproliferative activity against siRNA-induced BAX knock down human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4671912 | F | induction of apoptosis in siRNA-induced BAX knock down human HeLa cells at 3 uM after after 48 hr by annexin V FITC and propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4671913 | F | Induction of mitochondrial membrane potential loss in human HeLa cells after 24 hrs by TMRE staining based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4671915 | F | Induction of apoptosis in human HeLA cells at 0.3 to 1 uM after 48 hr by annexin V FITC and propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4671916 | F | Induction of apoptosis in human HeLA cells at 3 uM after 48 hr by annexin V FITC and propidium iodide staining based flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4671917 | F | Induction of apoptosis in human HeLA cells at 1 uM after 48 hr by laser confocal microscopic based TUNEL assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4671918 | F | Induction of apoptosis in human HeLa cells assessed as formation of apoptotic bodies at 1 uM after 6 to 36 hrs by fluorescence microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4671919 | F | Induction of apoptosis in human HeLa cells assessed as membrane blebbing at 1 uM after 6 to 36 hrs by fluorescence microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4671920 | F | Induction of apoptosis in human HeLa cells assessed as cellular shrinkage at 1 uM after 6 to 36 hrs by fluorescence microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4671921 | F | Potency index, ratio of IC50 for SAHA to test compound IC50 for antiproliferation activity against human HeLa cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4671922 | F | Potency index, ratio of IC50 for BSTA1 to test compound IC50 for antiproliferation activity against human HeLa cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4671923 | B | Activation of BAX in human HeLa cells assessed as confirmation activation at Bax6A7 after 6 to 12 hrs by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4671924 | B | Inhibition of class 1 HDAC in human HeLa cells assessed as increase in acetylation of H3 substrate at 0.3 to 3 uM after 6 to 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4671925 | F | Up regulation of BAX protein in human HeLa cells at 0.3 to 3 uM after 6 to 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4671926 | B | Inhibition of HDAC8 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA4671927 | B | Inhibition of HDAC2 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4671928 | B | Inhibition of HDAC1 (unknown origin) in using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA4671929 | B | Binding affinity to full length His-tagged Bcl-xl (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 mins by fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 20. | ALA4671930 | B | Binding affinity to full length His-tagged Mcl1 (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 mins by fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature |
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