# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4767829 | Binding | Displacement of [125l]-lodomelatonin from human MT1 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysis | Homo sapiens | 17 | ALA4765258 | cell-based format | Scientific Literature | |
2. | ALA4767830 | Binding | Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysis | Homo sapiens | 17 | ALA4765258 | cell-based format | Scientific Literature | |
3. | ALA4767831 | Binding | Displacement of [125l]-lodomelatonin from hamster brain cell QR2 incubated for 60 mins by scintillation counting analysis | Cricetinae | 12 | ALA4765258 | tissue-based format | Scientific Literature | |
4. | ALA4767834 | Functional | Antioxidant activity assessed as AAPH radical scavenging activity preincubated for 15 mins measured every min for 80 mins by ORAC-FL assay relative to trolox | 17 | ALA4765258 | assay format | Scientific Literature | ||
5. | ALA4767835 | Binding | Activation of NRF2 in human AREc32 cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 10 | ALA4765258 | cell-based format | Scientific Literature | |
6. | ALA4767836 | Binding | Binding affinity to human recombinant Keap1 Kelch domain expressed in Escherichia coli BL21 (DE3) by SPR assay | Homo sapiens | 7 | ALA4765258 | assay format | Scientific Literature | |
7. | ALA4767840 | ADME | Permeability of compound by PAMPA-BBB assay | 16 | ALA4765258 | assay format | Scientific Literature | ||
8. | ALA4767841 | Binding | Displacement of [125l]-lodomelatonin from human MT1 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysis relative to control | Homo sapiens | 7 | ALA4765258 | cell-based format | Scientific Literature |